Global Patent Index - EP 1019399 A1

EP 1019399 A1 2000-07-19 - ARYL THIOPHENE DERIVATIVES AS PDE IV INHIBITORS

Title (en)

ARYL THIOPHENE DERIVATIVES AS PDE IV INHIBITORS

Title (de)

ARYL THIOPHENE DERIVATE ALS PDE IV INHIBITOREN

Title (fr)

DERIVES D'ARYLTHIOPHENE UTILISES COMME INHIBITEURS DE LA PHOSPHODIESTERASE IV

Publication

EP 1019399 A1 (EN)

Application

EP 98946190 A

Priority

  • CA 9800931 W
  • GB 9808109 A
  • US 6091497 P

Abstract (en)

[origin: WO9918099A1] The invention encompasses the novel compound of Formula (I) useful in the treatment of diseases, including asthma, by raising the level of cyclic adenosine-3',5'-monophosphate (cAMP) through the inhibition of phosphodiesterase IV (PDE IV). The invention also encompasses certain pharmaceutical compositions and methods for treatment of diseases by inhibition of PDE IV, resulting in an elevation of cAMP, comprising the use of compounds of Formula (I).

IPC 1-7 (main, further and additional classification)

C07D 409/12; A61K 31/38; C07D 333/16; C07D 333/24; C07D 409/04; C07D 409/14; C07D 417/14

IPC 8 full level (invention and additional information)

C07D 333/18 (2006.01); A61K 31/381 (2006.01); A61K 31/443 (2006.01); A61K 31/4433 (2006.01); A61K 31/4436 (2006.01); A61K 31/497 (2006.01); A61K 31/506 (2006.01); A61P 11/06 (2006.01); A61P 43/00 (2006.01); C07D 333/16 (2006.01); C07D 333/24 (2006.01); C07D 333/34 (2006.01); C07D 405/12 (2006.01); C07D 409/04 (2006.01); C07D 409/12 (2006.01); C07D 409/14 (2006.01); C07D 417/14 (2006.01)

CPC (invention and additional information)

C07D 409/14 (2013.01); C07D 333/24 (2013.01); C07D 409/04 (2013.01); C07D 409/12 (2013.01); C07D 417/14 (2013.01)

Citation (search report)

See references of WO 9918099A1

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU NL PT SE

EPO simple patent family

WO 9918099 A1 19990415; WO 9918099 B1 19990527; AU 732406 B2 20010426; AU 9334798 A 19990427; CA 2305414 A1 19990415; EP 1019399 A1 20000719; JP 2001519347 A 20011023; JP 3409029 B2 20030519

INPADOC legal status


2003-01-02 [18D] DEEMED TO BE WITHDRAWN

- Effective date: 20020625

2001-04-18 [17Q] FIRST EXAMINATION REPORT

- Effective date: 20010301

2000-07-19 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 20000503

2000-07-19 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A1

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU NL PT SE

2000-07-19 [AX] REQUEST FOR EXTENSION OF THE EUROPEAN PATENT TO

- Free text: AL PAYMENT 20000503;LT PAYMENT 20000503;LV PAYMENT 20000503;MK PAYMENT 20000503;RO PAYMENT 20000503;SI PAYMENT 20000503