EP 1019411 A1 20000719 - PROCESS FOR SYNTHESIZING CARBAPENEM SIDE CHAIN INTERMEDIATES
Title (en)
PROCESS FOR SYNTHESIZING CARBAPENEM SIDE CHAIN INTERMEDIATES
Title (de)
VERFAHREN ZUR HERSTELLUNG VON ZWISCHENPRODUKTEN FÜR CARBAPENEM-SEITENKETTEN
Title (fr)
PROCEDE DE SYNTHETISATION D'INTERMEDIAIRES DE CARBAPENEM A CHAINE LATERALE
Publication
Application
Priority
- GB 9810184 A 19980513
- US 9813738 W 19980702
- US 5203297 P 19970709
Abstract (en)
[origin: WO9902531A1] A process of synthesizing a compound of formula (1) is described. A compound of formula (2) is reacted with diphenylphosphinic chloride to activate the carboxylic acid group, and then reacted with methanesulfonyl chloride to produce a compound of formula (4). Compound (4) is then reacted with a group II metal sulfide source in water to produce a compound of formula (1).
IPC 1-7
IPC 8 full level
C07D 207/16 (2006.01); C07D 409/12 (2006.01); C07D 495/08 (2006.01); C07F 9/572 (2006.01)
CPC (source: EP)
C07D 207/16 (2013.01); C07D 409/12 (2013.01); C07D 495/08 (2013.01); C07F 9/572 (2013.01)
Designated contracting state (EPC)
AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE
DOCDB simple family (publication)
WO 9902531 A1 19990121; AU 731586 B2 20010405; AU 8282198 A 19990208; CA 2294342 A1 19990121; CA 2294342 C 20060314; EP 1019411 A1 20000719; EP 1019411 A4 20030813; JP 2002504156 A 20020205
DOCDB simple family (application)
US 9813738 W 19980702; AU 8282198 A 19980702; CA 2294342 A 19980702; EP 98933069 A 19980702; JP 50875599 A 19980702