Global Patent Index - EP 1019427 A1

EP 1019427 A1 2000-07-19 - N?6 -SUBSTITUTED-ADENOSINE-5'-URONAMIDES AS ADENOSINE RECEPTOR MODULATORS

Title (en)

N?6 -SUBSTITUTED-ADENOSINE-5'-URONAMIDES AS ADENOSINE RECEPTOR MODULATORS

Title (de)

N6-SUBSTITUIERTE ADENOSIN-5'-URONAMIDE ALS ADENOSIN-REZEPTOR-MODULATOREN

Title (fr)

N?6 -SUBSTITUES-ADENOSINE-5'-URONAMIDES UTILES COMME MODULATEURS DE RECEPTEURS D'ADENOSINE

Publication

EP 1019427 A1 (EN)

Application

EP 98939156 A

Priority

  • US 9816053 W
  • US 5406497 P

Abstract (en)

[origin: WO9906053A1] A series of adenosine-5'-uronamide derivatives bearing N<6>-arylurea, alkarylurea, heteroarylurea, arylcarbonyl, alkarylcarbonyl or heteroarylcarbonyl groups which have affinity and, in some cases, selectivity for the adenosine A1 or A3 receptors are disclosed. These compounds can be used in a pharmaceutical composition to treat disorders caused by excessive activation of the A1 or A3 receptors, or can be used in a diagnostic application to determine the relative binding of other compounds to the A1 or A3 receptors.

IPC 1-7 (main, further and additional classification)

C07H 19/16; A61K 31/70

IPC 8 full level (invention and additional information)

C07H 19/167 (2006.01); A61K 31/7042 (2006.01); A61K 31/7052 (2006.01); A61K 31/7076 (2006.01); A61P 3/06 (2006.01); A61P 9/06 (2006.01); A61P 9/10 (2006.01); A61P 9/12 (2006.01); A61P 9/14 (2006.01); A61P 11/16 (2006.01); A61P 25/04 (2006.01); A61P 25/08 (2006.01); A61P 25/28 (2006.01); A61P 27/06 (2006.01); A61P 29/00 (2006.01); A61P 35/00 (2006.01); C07H 19/16 (2006.01); C07H 19/173 (2006.01)

CPC (invention and additional information)

C07H 19/16 (2013.01)

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

DOCDB simple family

WO 9906053 A1 19990211; AU 8764398 A 19990222; CA 2296485 A1 19990211; EP 1019427 A1 20000719; EP 1019427 A4 20000719; JP 2003517423 A 20030527