EP 1019427 A1 20000719 - N?6 -SUBSTITUTED-ADENOSINE-5'-URONAMIDES AS ADENOSINE RECEPTOR MODULATORS
Title (en)
N?6 -SUBSTITUTED-ADENOSINE-5'-URONAMIDES AS ADENOSINE RECEPTOR MODULATORS
Title (de)
N6-SUBSTITUIERTE ADENOSIN-5'-URONAMIDE ALS ADENOSIN-REZEPTOR-MODULATOREN
Title (fr)
N?6 -SUBSTITUES-ADENOSINE-5'-URONAMIDES UTILES COMME MODULATEURS DE RECEPTEURS D'ADENOSINE
Publication
Application
Priority
- US 9816053 W 19980729
- US 5406497 P 19970729
Abstract (en)
[origin: WO9906053A1] A series of adenosine-5'-uronamide derivatives bearing N<6>-arylurea, alkarylurea, heteroarylurea, arylcarbonyl, alkarylcarbonyl or heteroarylcarbonyl groups which have affinity and, in some cases, selectivity for the adenosine A1 or A3 receptors are disclosed. These compounds can be used in a pharmaceutical composition to treat disorders caused by excessive activation of the A1 or A3 receptors, or can be used in a diagnostic application to determine the relative binding of other compounds to the A1 or A3 receptors.
IPC 1-7
IPC 8 full level
C07H 19/167 (2006.01); A61K 31/7042 (2006.01); A61K 31/7052 (2006.01); A61K 31/7076 (2006.01); A61P 3/06 (2006.01); A61P 9/06 (2006.01); A61P 9/10 (2006.01); A61P 9/12 (2006.01); A61P 9/14 (2006.01); A61P 11/16 (2006.01); A61P 25/04 (2006.01); A61P 25/08 (2006.01); A61P 25/28 (2006.01); A61P 27/06 (2006.01); A61P 29/00 (2006.01); A61P 35/00 (2006.01); C07H 19/16 (2006.01); C07H 19/173 (2006.01)
CPC (source: EP)
A61P 3/06 (2017.12); A61P 9/06 (2017.12); A61P 9/10 (2017.12); A61P 9/12 (2017.12); A61P 9/14 (2017.12); A61P 11/16 (2017.12); A61P 25/04 (2017.12); A61P 25/08 (2017.12); A61P 25/28 (2017.12); A61P 27/06 (2017.12); A61P 29/00 (2017.12); A61P 35/00 (2017.12); C07H 19/16 (2013.01)
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9906053 A1 19990211; AU 8764398 A 19990222; CA 2296485 A1 19990211; EP 1019427 A1 20000719; EP 1019427 A4 20000719; JP 2003517423 A 20030527
DOCDB simple family (application)
US 9816053 W 19980729; AU 8764398 A 19980729; CA 2296485 A 19980729; EP 98939156 A 19980729; JP 2000504866 A 19980729