EP 1020446 A1 20000719 - NAPHTHALIMIDOBENZAMIDE DERIVATIVES
Title (en)
NAPHTHALIMIDOBENZAMIDE DERIVATIVES
Title (de)
NAPHTHIMIDOBENZAMID-DERIVATE
Title (fr)
DERIVES DE NAPHTALIMIDOBENZAMIDE
Publication
Application
Priority
- JP 9903574 W 19990702
- JP 18907898 A 19980703
Abstract (en)
The present invention relates to a naphthalimidobenzamide derivative represented by the following formula (1): <CHEM> (wherein, R<1> represents a hydrogen atom, etc., Y represents a hydrogen atom or -CON(R<4>)-A<2>-X<2>, R<2> and R<4> are the same or different and each independently represents a hydrogen atom, etc., A<1> and A<2> are the same or different and each independently represents an alkylene group which may be interrupted at least once by -N(R<3>)- (R<3> representing a hydrogen atom, etc.) and X<1> and X<2> are the same or different and each independently represents a (hetero)aryl group which may have a substituent, etc.) or salt thereof; and a pharmaceutical comprising it as an effective ingredient. The compound is useful as an antitumor agent and the like.
IPC 1-7
C07D 221/14; C07D 401/12; C07D 401/14; A61K 31/47; A61K 31/495; A61K 31/535
IPC 8 full level
C07D 221/14 (2006.01); C07D 401/14 (2006.01); C07D 471/04 (2006.01); C07D 519/00 (2006.01)
CPC (source: EP KR US)
A61P 35/00 (2018.01 - EP); C07D 221/14 (2013.01 - EP KR US); C07D 401/14 (2013.01 - EP US); C07D 471/04 (2013.01 - EP US)
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
EP 1020446 A1 20000719; EP 1020446 A4 20011107; EP 1020446 B1 20060315; AT E320417 T1 20060415; AU 4396399 A 20000124; AU 727591 B2 20001214; CA 2300069 A1 20000113; CA 2300069 C 20060117; DE 69930383 D1 20060511; DE 69930383 T2 20061005; JP 3357662 B2 20021216; KR 100364205 B1 20021211; KR 20010023464 A 20010326; US 6300331 B1 20011009; WO 0001672 A1 20000113
DOCDB simple family (application)
EP 99926895 A 19990702; AT 99926895 T 19990702; AU 4396399 A 19990702; CA 2300069 A 19990702; DE 69930383 T 19990702; JP 2000558077 A 19990702; JP 9903574 W 19990702; KR 20007002109 A 20000229; US 50804400 A 20000303