Global Patent Index - EP 1021185 A1

EP 1021185 A1 2000-07-26 - DIDHYDROPYRIMIDINES AND USES THEREOF

Title (en)

DIDHYDROPYRIMIDINES AND USES THEREOF

Title (de)

DIHYDROPYRIMIDINE UND IHRE VERWENDUNGEN.

Title (fr)

DIHYDROPYRIMIDINES ET LEURS EMPLOIS

Publication

EP 1021185 A1 (EN)

Application

EP 97924745 A

Priority

  • US 9708335 W
  • US 64876896 A
  • US 1780196 P

Abstract (en)

[origin: WO9742956A1] This invention is directed to dihydropyrimidine compounds which are selective antagonists for human alpha 1A receptors. This invention is also related to uses of these compounds for lowering intraocular pressure, inhibiting cholesterol synthesis, relaxing lower urinary tract tissue, the treatment of benign prostatic hyperplasia, impotency, cardiac arrhythmia and for the treatment of any disease where the antagonism of the alpha 1A receptor may be useful. The invention further provides a pharmaceutical composition comprising a therapeutically effective amount of the above-defined compounds and a pharmaceutically acceptable carrier.

IPC 1-7 (main, further and additional classification)

A61K 31/505; C07D 239/22; C07D 239/36; C07D 401/06; C07D 401/12; C07D 401/14

IPC 8 full level (invention and additional information)

C07D 239/28 (2006.01); A61K 31/00 (2006.01); A61K 31/505 (2006.01); A61K 31/506 (2006.01); A61K 31/513 (2006.01); A61K 31/519 (2006.01); A61K 31/529 (2006.01); A61P 3/00 (2006.01); A61P 3/06 (2006.01); A61P 9/00 (2006.01); A61P 9/06 (2006.01); A61P 13/00 (2006.01); A61P 13/08 (2006.01); A61P 15/00 (2006.01); A61P 15/10 (2006.01); A61P 25/00 (2006.01); A61P 25/02 (2006.01); C07D 239/22 (2006.01); C07D 239/36 (2006.01); C07D 401/06 (2006.01); C07D 401/10 (2006.01); C07D 401/12 (2006.01); C07D 401/14 (2006.01); C07D 403/06 (2006.01); C07D 403/12 (2006.01); C07D 405/14 (2006.01); C07D 413/14 (2006.01); C07D 451/02 (2006.01); C07D 451/06 (2006.01); C07D 491/04 (2006.01); C07D 491/048 (2006.01); C07D 521/00 (2006.01)

CPC (invention and additional information)

C07D 239/22 (2013.01); A61K 31/506 (2013.01); C07D 231/12 (2013.01); C07D 233/56 (2013.01); C07D 249/08 (2013.01); C07D 401/06 (2013.01); C07D 401/10 (2013.01); C07D 401/12 (2013.01); C07D 401/14 (2013.01); C07D 413/14 (2013.01); C07D 451/06 (2013.01); C07D 491/04 (2013.01)

Designated contracting state (EPC)

AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

EPO simple patent family

WO 9742956 A1 19971120; AU 3008297 A 19971205; AU 727972 B2 20010104; CA 2253862 A1 19971120; EP 1021185 A1 20000726; EP 1021185 A4 20050907; JP 2000506904 A 20000606

INPADOC legal status


2006-05-03 [18D] DEEMED TO BE WITHDRAWN

- Effective date: 20051015

2005-09-07 [A4] SUPPLEMENTARY SEARCH REPORT

- Effective date: 20050722

2005-06-15 [RIC1] CLASSIFICATION (CORRECTION)

- IPC: 7A 61K 31/505 A

2005-06-15 [RIC1] CLASSIFICATION (CORRECTION)

- IPC: 7C 07D 239/36 B

2005-06-15 [RIC1] CLASSIFICATION (CORRECTION)

- IPC: 7C 07D 239/22 B

2005-06-15 [RIC1] CLASSIFICATION (CORRECTION)

- IPC: 7C 07D 401/12 B

2005-06-15 [RIC1] CLASSIFICATION (CORRECTION)

- IPC: 7C 07D 401/06 B

2005-06-15 [RIC1] CLASSIFICATION (CORRECTION)

- IPC: 7C 07D 401/14 B

2000-07-26 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 19981130

2000-07-26 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A1

- Designated State(s): AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE