Global Patent Index - EP 1021401 A1

EP 1021401 A1 20000726 - CALCITRIOL DERIVATIVES AND THEIR USES

Title (en)

CALCITRIOL DERIVATIVES AND THEIR USES

Title (de)

CALCITRIOL DERIVATE UND IHRE VERWENDUNGEN

Title (fr)

DERIVES DE CALCITRIOL ET LEURS UTILISATIONS

Publication

EP 1021401 A1 20000726 (EN)

Application

EP 96933853 A 19960920

Priority

  • US 9615184 W 19960920
  • US 53140395 A 19950921
  • US 53186795 A 19950921

Abstract (en)

[origin: WO9711053A1] A method of treating metabolic bone diseases such as osteoporosis, as well as other disease states treatable with vitamin D compounds, comprises administering an effective amount of one or more modified vitamin D compounds. The modified compound contains a typical vitamin D nucleus but with in vivo hydrolyzable groups at one or more of the 1, 3 and 25 carbon positions. The time of conversion of the modified compound to its active form, such as calcitriol, can be regulated to thus provide controlled release of the compound in vivo over time, by changing or modifying the hydrolyzable groups.

IPC 1-7

C07C 401/00; A61K 31/59

IPC 8 full level

A61K 31/00 (2006.01); A61P 3/00 (2006.01); A61K 31/59 (2006.01); A61P 3/02 (2006.01); A61P 7/00 (2006.01); A61P 19/00 (2006.01); A61P 19/08 (2006.01); C07C 401/00 (2006.01)

CPC (source: EP KR)

A61K 31/59 (2013.01 - KR); A61P 3/00 (2018.01 - EP); A61P 3/02 (2018.01 - EP); A61P 7/00 (2018.01 - EP); A61P 19/00 (2018.01 - EP); A61P 19/08 (2018.01 - EP); C07C 401/00 (2013.01 - EP KR)

Designated contracting state (EPC)

AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

DOCDB simple family (publication)

WO 9711053 A1 19970327; AU 717238 B2 20000323; AU 7242696 A 19970409; CA 2229316 A1 19970327; CA 2229316 C 20050412; EP 1021401 A1 20000726; HU P9802303 A2 19990201; HU P9802303 A3 19990528; JP 3372259 B2 20030127; JP H11511475 A 19991005; KR 100327922 B1 20020509; KR 19990063628 A 19990726; MX 9801943 A 19980830; NO 981282 D0 19980320; NO 981282 L 19980522; NZ 319819 A 20000228; NZ 501318 A 20010727

DOCDB simple family (application)

US 9615184 W 19960920; AU 7242696 A 19960920; CA 2229316 A 19960920; EP 96933853 A 19960920; HU P9802303 A 19960920; JP 51294597 A 19960920; KR 19980702077 A 19980320; MX 9801943 A 19980312; NO 981282 A 19980320; NZ 31981996 A 19960920; NZ 50131896 A 19960920