Global Patent Index - EP 1021436 A1

EP 1021436 A1 2000-07-26 - ETHYL 4-(8-CHLORO-5, 6-DIHYDRO-11H- BENZO 5,6 CYCLOHEPTA 1,2-b PYRIDIN -11-YLIDENE)-1- PIPERIDENE CARBOXYLATE POLYMORPH

Title (en)

ETHYL 4-(8-CHLORO-5, 6-DIHYDRO-11H- BENZO 5,6 CYCLOHEPTA 1,2-b PYRIDIN -11-YLIDENE)-1- PIPERIDENE CARBOXYLATE POLYMORPH

Title (de)

ETHYL4-(8-CHLORO-5,6-DIHYDRO-11H-BENZO¬5,6 CYCCLOHEPTA¬1,2 PYRIDIN-11-YLIDENE)-1-PIPERIDENCARBOXYLATPOLYMORPPH

Title (fr)

POLYMORPHE D'ETHYL 4-(8-CHLORO-5, 6,-DIHYDRO-11H- BENZO 5,6 CYCLOHEPTA 1,2-b PYRIDINE -11-YLIDENE)-1- PIPERIDENE CARBOXYLATE

Publication

EP 1021436 A1 (EN)

Application

EP 98950916 A

Priority

  • US 9820919 W
  • US 94888697 A

Abstract (en)

[origin: WO9919322A1] A polymorph form 2 of ethyl 4-(8-chloro-5, 6-dihydro-11H- benzo[5,6]cyclohepta [1,2-b]pyridin -11-ylidene)-1- piperidene carboxylate (hereinafter "loratadine") represented by formula (I). Pharmaceutical composition containing the polymorph form 2, and methods of using the polymorph form 2 to treat allergic reactions in mammals such as man are disclosed.

IPC 1-7 (main, further and additional classification)

C07D 401/04; A61K 31/445

IPC 8 full level (invention and additional information)

A61K 31/4427 (2006.01); A61K 31/4545 (2006.01); A61P 37/08 (2006.01); C07D 401/04 (2006.01)

CPC (invention and additional information)

C07D 401/04 (2013.01)

Citation (search report)

See references of WO 9919322A1

Designated contracting state (EPC)

AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE

Designated extension state (EPC)

LT LV RO

EPO simple patent family

WO 9919322 A1 19990422; AU 9683798 A 19990503; CA 2305801 A1 19990422; EP 1021436 A1 20000726; JP 2001519428 A 20011023

INPADOC legal status


2007-11-14 [RTI1] TITLE (CORRECTION)

- Ref Legal Event Code: RTI1

- Free Format Text: ETHYL 4-(8-CHLORO-5, 6-DIHYDRO-11H- BENZO 5,6 CYCLOHEPTA 1,2-B PYRIDIN -11-YLIDENE)-1- PIPERIDENE CARBOXYLATE POLYMORPH

2004-05-12 [18D] DEEMED TO BE WITHDRAWN

- Ref Legal Event Code: 18D

- Effective date: 20031106

2002-06-12 [17Q] FIRST EXAMINATION REPORT

- Ref Legal Event Code: 17Q

- Effective date: 20020424

2000-07-26 [17P] REQUEST FOR EXAMINATION FILED

- Ref Legal Event Code: 17P

- Effective date: 20000410

2000-07-26 [AK] DESIGNATED CONTRACTING STATES:

- Ref Legal Event Code: AK

- Designated State(s): AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE

2000-07-26 [AX] REQUEST FOR EXTENSION OF THE EUROPEAN PATENT TO

- Ref Legal Event Code: AX

- Free Format Text: LT PAYMENT 20000410;LV PAYMENT 20000410;RO PAYMENT 20000410