EP 1021531 A2 20000726 - HUMAN PROTEINS HAVING TRANSMEMBRANE DOMAINS AND cDNAs ENCODING THESE PROTEINS
Title (en)
HUMAN PROTEINS HAVING TRANSMEMBRANE DOMAINS AND cDNAs ENCODING THESE PROTEINS
Title (de)
HUMANE PROTEINE MIT TRANSMEMBRAN-DOMÄNEN UND DNAS DAFÜR KODIEREND
Title (fr)
PROTEINES HUMAINES COMPORTANT DES DOMAINES TRANSMEMBRANAIRES ET ADN CODANT CES PROTEINES
Publication
Application
Priority
- JP 9804474 W 19981005
- JP 27626997 A 19971008
Abstract (en)
[origin: WO9918202A2] The invention provides human proteins having transmembrane domains and cDNAs coding for these proteins as well as eucaryotic cells expressing said cDNAs. All of the proteins exist in the cell membrane, so that they are considered to be proteins controlling the proliferation and the differentiation of the cells. Accordingly, the proteins can be employed as pharmaceuticals such as carcinostatic agents relating to the control of the proliferation and the differentiation of the cells or as antigens for preparing antibodies against said proteins. The cDNAs can be utilized as probes for the gene diagnosis and gene sources for the gene therapy. Furthermore, the cDNAs can be utilized for large-scale expression of said proteins. Cells, wherein these membrane protein genes are introduced and membrane proteins are expressed in large amounts, can be utilized for detection of the corresponding ligands, screening of novel low-molecular pharmaceuticals, and so on.
IPC 1-7
IPC 8 full level
C07K 14/705 (2006.01); C12N 15/12 (2006.01)
CPC (source: EP)
C07K 14/705 (2013.01)
Citation (search report)
See references of WO 9918202A2
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9918202 A2 19990415; WO 9918202 A3 19990805; AU 9283198 A 19990427; CA 2308120 A1 19990415; EP 1021531 A2 20000726
DOCDB simple family (application)
JP 9804474 W 19981005; AU 9283198 A 19981005; CA 2308120 A 19981005; EP 98945602 A 19981005