Global Patent Index - EP 1023078 A1

EP 1023078 A1 2000-08-02 - PRECIPITATION OF GROWTH-FACTOR-ENRICHED FIBRINOGEN CONCENTRATE FROM PLATELET RICH PLASMA

Title (en)

PRECIPITATION OF GROWTH-FACTOR-ENRICHED FIBRINOGEN CONCENTRATE FROM PLATELET RICH PLASMA

Title (de)

AUSFÄLLUNG VON WACHSTUMSFAKTOR ANGEREICHERTEM FIBRINOGENKONZENTRAT AUS BLUTPLÄTTCHEN-REICHEM PLASMA

Title (fr)

PRECIPITATION D'UN CONCENTRE DE FIBRINOGENE ENRICHI D'UN FACTEUR DE CROISSANCE OBTENU A PARTIR DE PLASMA ENRICHI EN PLAQUETTES

Publication

EP 1023078 A1 (EN)

Application

EP 98953467 A

Priority

  • US 9821626 W
  • US 6226497 P

Abstract (en)

[origin: WO9920288A1] Increased fibrinogen yields are obtained by adding a precipitating agent to plasma having a high platelet concentration, such as platelet rich plasma. The precipitating agent may be any of several known agents, including polyethylene glycol and ammonium sulfate. The platelet rich plasma is obtained in the preferred embodiment by subjecting plasma to "soft spin" centrifugation of about 580G. An automatic, multiple decanting and multiple-speed centrifuge is preferably used to separate anti-coagulated whole blood into the platelet rich plasma component and red blood cells. The proteins, preferably fibrinogen, FXIII, and FVIII, in the platelet rich component are precipitated, and the proteins and platelets are then concentrated by further centrifugation.

IPC 1-7 (main, further and additional classification)

A61K 35/16; B01D 21/26; C07K 14/75; C12Q 1/56

IPC 8 full level (invention and additional information)

C12Q 1/56 (2006.01); A61K 35/14 (2006.01); A61K 35/16 (2006.01); A61K 38/36 (2006.01); A61K 38/43 (2006.01); A61L 26/00 (2006.01); B01D 17/02 (2006.01); B01D 21/01 (2006.01); B01D 21/26 (2006.01); C07K 1/30 (2006.01); C07K 14/75 (2006.01); G01N 33/50 (2006.01)

CPC (invention and additional information)

G01N 33/5094 (2013.01); A61K 38/363 (2013.01); A61L 26/0042 (2013.01); B01D 17/0217 (2013.01); B01D 21/01 (2013.01); B01D 21/262 (2013.01); B01D 21/34 (2013.01); B01D 2221/10 (2013.01)

Combination set (CPC)

  1. B01D 17/0217 + B01D 17/047
  2. B01D 21/01 + B01D 21/26

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

EPO simple patent family

WO 9920288 A1 19990429; CA 2306629 A1 19990429; CN 1113656 C 20030709; CN 1276725 A 20001213; EP 1023078 A1 20000802; EP 1023078 A4 20040929; JP 2001520198 A 20011030

INPADOC legal status


2008-08-20 [18D] DEEMED TO BE WITHDRAWN

- Effective date: 20080301

2007-05-02 [17Q] FIRST EXAMINATION REPORT

- Effective date: 20050428

2005-06-15 [17Q] FIRST EXAMINATION REPORT

- Effective date: 20050428

2004-09-29 [A4] SUPPLEMENTARY SEARCH REPORT

- Effective date: 20040812

2000-08-02 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 20000414

2000-08-02 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A1

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE