EP 1023268 A1 20000802 - ISOQUINOLINES AS UROKINASE INHIBITORS
Title (en)
ISOQUINOLINES AS UROKINASE INHIBITORS
Title (de)
ISOCHINOLIN DERIVATE ALS UROKINASE INHIBITOREN
Title (fr)
ISOQUINOLINES EN TANT QU'INHIBITEURS DE L'UROKINASE
Publication
Application
Priority
- EP 9806353 W 19981005
- GB 9721964 A 19971016
Abstract (en)
[origin: WO9920608A1] Compounds of formula (I) and pharmaceutically acceptable salts thereof, wherein one of R<1> and R<2> is H and the other is N=C(NH2)2 or NHC(=NH)NH2, and the other substituents are as defined herein, are urokinase (uPA) inhibitors.
IPC 1-7
C07D 217/22; C07D 405/04; C07D 401/06; C07D 409/04; C07D 491/04; A61K 31/47
IPC 8 full level
A61K 31/472 (2006.01); A61K 31/4725 (2006.01); A61K 31/4741 (2006.01); A61K 31/497 (2006.01); A61K 31/5377 (2006.01); A61P 15/08 (2006.01); A61P 17/02 (2006.01); A61P 19/00 (2006.01); A61P 19/02 (2006.01); A61P 29/00 (2006.01); A61P 35/04 (2006.01); A61P 43/00 (2006.01); C07D 217/22 (2006.01); C07D 217/24 (2006.01); C07D 401/04 (2006.01); C07D 401/06 (2006.01); C07D 401/12 (2006.01); C07D 405/04 (2006.01); C07D 409/04 (2006.01); C07D 491/04 (2006.01); C07D 491/056 (2006.01); C07D 521/00 (2006.01)
CPC (source: EP KR US)
A61K 31/472 (2013.01 - KR); A61K 31/4725 (2013.01 - KR); A61P 15/08 (2018.01 - EP); A61P 17/02 (2018.01 - EP); A61P 19/00 (2018.01 - EP); A61P 19/02 (2018.01 - EP); A61P 29/00 (2018.01 - EP); A61P 35/04 (2018.01 - EP); A61P 43/00 (2018.01 - EP); C07D 207/48 (2013.01 - KR); C07D 217/16 (2013.01 - KR); C07D 217/22 (2013.01 - EP KR US); C07D 217/24 (2013.01 - KR); C07D 217/26 (2013.01 - KR); C07D 231/12 (2013.01 - EP US); C07D 233/56 (2013.01 - EP US); C07D 249/08 (2013.01 - EP US); C07D 295/26 (2013.01 - KR); C07D 401/04 (2013.01 - EP US); C07D 401/12 (2013.01 - KR); C07D 405/04 (2013.01 - EP US); C07D 409/04 (2013.01 - EP US); C07D 413/12 (2013.01 - KR); C07D 491/04 (2013.01 - EP US)
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU NL PT SE
DOCDB simple family (publication)
WO 9920608 A1 19990429; AP 959 A 20010417; AP 9801366 A0 19981231; AR 015964 A1 20010530; AT E240943 T1 20030615; AU 1150899 A 19990510; AU 727315 B2 20001207; BG 104328 A 20001229; BR 9812922 A 20000808; CA 2306782 A1 19990429; CA 2306782 C 20050517; CN 1275979 A 20001206; CO 4990959 A1 20001226; DE 69814894 D1 20030626; DE 69814894 T2 20031224; DK 1023268 T3 20030610; DZ 2624 A1 20030308; EA 002632 B1 20020829; EA 200000320 A1 20001030; EP 1023268 A1 20000802; EP 1023268 B1 20030521; ES 2197514 T3 20040101; GB 9721964 D0 19971217; GT 199800159 A 20000401; HN 1998000158 A 19990209; HR P20000217 A2 20001031; HU P0004491 A2 20010328; HU P0004491 A3 20021028; ID 23913 A 20000525; IL 135122 A0 20010520; IS 5412 A 20000321; JP 2001520221 A 20011030; JP 3600794 B2 20041215; KR 20010031163 A 20010416; MA 26552 A1 20041220; NO 20001924 D0 20000413; NO 20001924 L 20000615; NZ 503390 A 20020328; OA 11348 A 20031218; PA 8461601 A1 20000524; PE 121299 A1 19991201; PL 340035 A1 20010115; PT 1023268 E 20030930; SK 4872000 A3 20011203; TN SN98185 A1 20050315; TR 200001010 T2 20000921; US 6248738 B1 20010619; UY 25211 A1 20001229; UY 25291 A1 19990719; YU 21100 A 20021115; ZA 989412 B 20000417
DOCDB simple family (application)
EP 9806353 W 19981005; AP 9801366 A 19981019; AR P980105113 A 19981014; AT 98954357 T 19981005; AU 1150899 A 19981005; BG 10432800 A 20000411; BR 9812922 A 19981005; CA 2306782 A 19981005; CN 98810108 A 19981005; CO 98060365 A 19981016; DE 69814894 T 19981005; DK 98954357 T 19981005; DZ 980234 A 19981014; EA 200000320 A 19981005; EP 98954357 A 19981005; ES 98954357 T 19981005; GB 9721964 A 19971016; GT 199800159 A 19981009; HN 1998000158 A 19981008; HR P20000217 A 20000414; HU P0004491 A 19981005; ID 20000691 A 19981005; IL 13512298 A 19981005; IS 5412 A 20000321; JP 2000516950 A 19981005; KR 20007004083 A 20000415; MA 25298 A 19981014; NO 20001924 A 20000413; NZ 50339098 A 19981005; OA 1200000102 A 20000407; PA 8461601 A 19981012; PE 00097398 A 19981015; PL 34003598 A 19981005; PT 98954357 T 19981005; SK 4872000 A 19981005; TN SN98185 A 19981014; TR 200001010 T 19981005; US 42449700 A 20000530; UY 25211 A 19981015; UY 25291 A 19981208; YU 21100 A 19981005; ZA 989412 A 19981015