Global Patent Index - EP 1023270 A1

EP 1023270 A1 2000-08-02 - INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE

Title (en)

INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE

Title (de)

INHIBITOREN DER FARNESYL-PROTEIN-TRANSFERASE

Title (fr)

INHIBITEURS DE FARNESYL-PROTEINE TRANSFERASE

Publication

EP 1023270 A1 (EN)

Application

EP 98951061 A

Priority

  • GB 9806432 A
  • US 9821599 W
  • US 6434297 P

Abstract (en)

[origin: WO9920609A1] The present invention is directed to compounds which inhibit farnesyl-protein transferase (FTase) and the farnesylation of the oncogene protein Ras. The invention is further directed to chemotherapeutic compositions containing the compounds of this invention and methods for inhibiting farnesyl-protein transferase and the farnesylation of the oncogene protein Ras.

IPC 1-7 (main, further and additional classification)

C07D 223/10; A61K 31/495; A61K 31/50; A61K 31/55; C07D 267/22; C07D 281/18; C07D 291/00; C07D 337/16; C07D 487/00; C07D 491/00; C07D 513/00

IPC 8 full level (invention and additional information)

C07D 487/08 (2006.01); C07D 498/08 (2006.01)

CPC (invention and additional information)

C07D 487/08 (2013.01)

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU NL PT SE

EPO simple patent family

WO 9920609 A1 19990429; AU 9695198 A 19990510; CA 2306312 A1 19990429; EP 1023270 A1 20000802; EP 1023270 A4 20010418

INPADOC legal status


2001-12-12 [18D] DEEMED TO BE WITHDRAWN

- Ref Legal Event Code: 18D

- Effective date: 20010518

2001-04-18 [A4] SUPPLEMENTARY SEARCH REPORT

- Ref Legal Event Code: A4

- Effective date: 20010302

2001-04-18 [AK] DESIGNATED CONTRACTING STATES:

- Ref Legal Event Code: AK

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU NL PT SE

2001-04-18 [RIC1] CLASSIFICATION (CORRECTION)

- Ref Legal Event Code: RIC1

- Free Format Text: 7C 07D 223/10 A, 7C 07D 267/22 B, 7C 07D 281/18 B, 7C 07D 291/00 B, 7C 07D 337/16 B, 7C 07D 487/00 B, 7C 07D 513/00 B, 7C 07D 491/00 B, 7A 61K 31/55 B, 7A 61K 31/495 B, 7A 61P 35/00 B

2000-08-02 [17P] REQUEST FOR EXAMINATION FILED

- Ref Legal Event Code: 17P

- Effective date: 20000517

2000-08-02 [AK] DESIGNATED CONTRACTING STATES:

- Ref Legal Event Code: AK

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU NL PT SE

2000-08-02 [AX] REQUEST FOR EXTENSION OF THE EUROPEAN PATENT TO

- Ref Legal Event Code: AX

- Free Format Text: AL PAYMENT 20000517;LT PAYMENT 20000517;LV PAYMENT 20000517;MK PAYMENT 20000517;RO PAYMENT 20000517;SI PAYMENT 20000517