EP 1023270 A1 20000802 - INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE
Title (en)
INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE
Title (de)
INHIBITOREN DER FARNESYL-PROTEIN-TRANSFERASE
Title (fr)
INHIBITEURS DE FARNESYL-PROTEINE TRANSFERASE
Publication
Application
Priority
- GB 9806432 A 19980325
- US 9821599 W 19981013
- US 6434297 P 19971017
Abstract (en)
[origin: WO9920609A1] The present invention is directed to compounds which inhibit farnesyl-protein transferase (FTase) and the farnesylation of the oncogene protein Ras. The invention is further directed to chemotherapeutic compositions containing the compounds of this invention and methods for inhibiting farnesyl-protein transferase and the farnesylation of the oncogene protein Ras.
IPC 1-7
C07D 223/10; C07D 267/22; C07D 281/18; C07D 291/00; C07D 337/16; C07D 487/00; C07D 513/00; C07D 491/00; A61K 31/55; A61K 31/495; A61K 31/50
IPC 8 full level
C07D 487/08 (2006.01); C07D 498/08 (2006.01)
CPC (source: EP)
A61P 35/00 (2017.12); C07D 487/08 (2013.01)
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU NL PT SE
DOCDB simple family (publication)
WO 9920609 A1 19990429; AU 9695198 A 19990510; CA 2306312 A1 19990429; EP 1023270 A1 20000802; EP 1023270 A4 20010418
DOCDB simple family (application)
US 9821599 W 19981013; AU 9695198 A 19981013; CA 2306312 A 19981013; EP 98951061 A 19981013