EP 1023270 A4 20010418 - INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE
Title (en)
INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE
Title (de)
INHIBITOREN DER FARNESYL-PROTEIN-TRANSFERASE
Title (fr)
INHIBITEURS DE FARNESYL-PROTEINE TRANSFERASE
Publication
Application
Priority
- GB 9806432 A 19980325
- US 9821599 W 19981013
- US 6434297 P 19971017
Abstract (en)
[origin: WO9920609A1] The present invention is directed to compounds which inhibit farnesyl-protein transferase (FTase) and the farnesylation of the oncogene protein Ras. The invention is further directed to chemotherapeutic compositions containing the compounds of this invention and methods for inhibiting farnesyl-protein transferase and the farnesylation of the oncogene protein Ras.
IPC 1-7
C07D 223/10; C07D 267/22; C07D 281/18; C07D 291/00; C07D 337/16; C07D 487/00; C07D 513/00; C07D 491/00; A61K 31/55; A61K 31/495; A61P 35/00
IPC 8 full level
C07D 487/08 (2006.01); C07D 498/08 (2006.01)
CPC (source: EP)
A61P 35/00 (2017.12); C07D 487/08 (2013.01)
Citation (search report)
- [X] WO 9736889 A1 19971009 - MERCK & CO INC [US], et al
- [X] WO 9736879 A1 19971009 - MERCK & CO INC [US], et al
- See references of WO 9920609A1
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU NL PT SE
DOCDB simple family (publication)
WO 9920609 A1 19990429; AU 9695198 A 19990510; CA 2306312 A1 19990429; EP 1023270 A1 20000802; EP 1023270 A4 20010418
DOCDB simple family (application)
US 9821599 W 19981013; AU 9695198 A 19981013; CA 2306312 A 19981013; EP 98951061 A 19981013