Global Patent Index - EP 1023281 A4

EP 1023281 A4 20000802 - HIV INTEGRASE INHIBITORS

Title (en)

HIV INTEGRASE INHIBITORS

Title (de)

HIV-INTEGRASE-INHIBITOREN

Title (fr)

INHIBITEURS DE LA VIH INTEGRASE

Publication

EP 1023281 A4 20000802 (EN)

Application

EP 98904970 A 19980203

Priority

  • GB 9707492 A 19970414
  • US 9802292 W 19980203
  • US 3690297 P 19970206

Abstract (en)

[origin: WO9834932A1] Natural products such as certain chaetochromins are described. These compounds are useful in the inhibition of HIV integrase, the prevention or treatment of infection by HIV and the treatment of AIDS, either as compounds, pharmaceutically acceptable salts, pharmaceutical composition ingredients, whether or not in combination with other antivirals, immunomodulators, antibiotics or vaccines. Methods of treating AIDS and methods of preventing or treating infection by HIV are also described.

IPC 1-7

C07D 321/00; C07D 311/92; A01N 43/16; A01N 43/02; A61K 31/35; A61K 31/335; C07D 407/10

IPC 8 full level

A61K 31/495 (2006.01); A61K 45/06 (2006.01); C07D 311/80 (2006.01); C07D 405/04 (2006.01)

CPC (source: EP)

A61K 31/495 (2013.01); A61K 45/06 (2013.01); C07D 311/80 (2013.01); C07D 405/04 (2013.01)

Citation (search report)

  • [Y] KOYAMA K. NATORI S. IITAKA Y.: "configuration of chaetochromin a and related bis-naphtho-gamma-pyrone mold metabolites", CHEMICAL & PHARMACEUTICAL BULLETIN, vol. 35, 1987, pages 4049 - 4055, XP000882789
  • [Y] TSUCHIYA T. SEKITA S. KOYAMA K. NATORIS. TAKAHASHI A: "effect of chaetochromin D and ustilaginoidin a bisnaphtho-gamma-pyrone derivatives on the mouse embryo limb bud and midbrain cells in culture", CONGENITAL ANOMALIES, vol. 27, 1987, pages 245 - 250, XP000881950
  • [Y] KOYAMA K. NATORI S.: "isolation from natural product", CHEM.PHARM.BULL., vol. 35, no. 2, 1987, pages 578 - 584, XP002135522
  • See references of WO 9834932A1

Designated contracting state (EPC)

AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE

DOCDB simple family (publication)

WO 9834932 A1 19980813; AU 6271098 A 19980826; CA 2280518 A1 19980813; EP 1023281 A1 20000802; EP 1023281 A4 20000802

DOCDB simple family (application)

US 9802292 W 19980203; AU 6271098 A 19980203; CA 2280518 A 19980203; EP 98904970 A 19980203