EP 1023323 A1 20000802 - NOVEL VITAMIN D RECEPTOR RELATED POLYPEPTIDES, NUCLEIC ACID SEQUENCE ENCODING THE SAME AND USES THEREOF
Title (en)
NOVEL VITAMIN D RECEPTOR RELATED POLYPEPTIDES, NUCLEIC ACID SEQUENCE ENCODING THE SAME AND USES THEREOF
Title (de)
VITAMIN D REZEPTOR-VERWANDTE POLYPEPTIDE, NUKLEINSÄURESEQUENZ WELCHE FÜR DIESE KODIERT UND ANWENDUNGEN DESRELBEN
Title (fr)
NOUVEAUX POLYPEPTIDES APPARENTES AU RECEPTEUR DE VITAMINE D, SEQUENCE D'ACIDE NUCLEIQUE CODANT CES POLYPEPTIDES ET UTILISATION DE CES DERNIERS
Publication
Application
Priority
- SE 9801548 W 19980831
- SE 9703745 A 19971014
- SE 9801148 A 19980331
Abstract (en)
[origin: WO9919354A1] The present invention relates to novel vitamin D receptor related (VDRR) polypeptides, and formulations containing the same. Nucleic acid sequences encoding the VDRR polypeptides, expression vectors containing such sequences and host cells transformed with such expression vectors are also disclosed, as are methods for the expression of the novel VDRR polypeptides of the invention. The invention further relates to VDRR polypeptides for use as medicaments, and use of substances affecting VDRR signal transduction for the manufacture of medicaments for treating metabolic, proliferative or inflammatory conditions. The present invention also relates to methods for identifying clones encoding a VDRR polypeptide, methods for identifying ligands to a VDRR and methods for identifying substances for treatment of conditions affected by a VDRR polypeptide. More specifically, the novel VDRR polypeptide can be the polypeptide designated VDRR gamma , which may be regulated by any small chemical molecule similar in structure to known ligands for nuclear receptors.
IPC 1-7
IPC 8 full level
G01N 33/50 (2006.01); A61K 38/00 (2006.01); A61K 45/00 (2006.01); A61K 48/00 (2006.01); A61P 1/14 (2006.01); A61P 3/00 (2006.01); A61P 3/04 (2006.01); A61P 3/06 (2006.01); A61P 3/10 (2006.01); A61P 5/18 (2006.01); A61P 19/02 (2006.01); A61P 19/10 (2006.01); A61P 29/00 (2006.01); A61P 35/00 (2006.01); A61P 43/00 (2006.01); C07K 14/72 (2006.01); C12N 5/10 (2006.01); C12N 15/09 (2006.01); C12P 21/02 (2006.01); C12P 21/08 (2006.01); C12Q 1/68 (2006.01); G01N 33/15 (2006.01); A61K 39/00 (2006.01)
CPC (source: EP KR US)
A61P 1/14 (2018.01 - EP); A61P 3/00 (2018.01 - EP); A61P 3/04 (2018.01 - EP); A61P 3/06 (2018.01 - EP); A61P 3/10 (2018.01 - EP); A61P 5/18 (2018.01 - EP); A61P 19/02 (2018.01 - EP); A61P 19/10 (2018.01 - EP); A61P 29/00 (2018.01 - EP); A61P 35/00 (2018.01 - EP); A61P 43/00 (2018.01 - EP); C07K 14/705 (2013.01 - KR); C07K 14/721 (2013.01 - EP); A61K 38/00 (2013.01 - EP); A61K 39/00 (2013.01 - EP KR US); A61K 48/00 (2013.01 - EP)
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
Designated extension state (EPC)
AL LT LV MK RO SI
DOCDB simple family (publication)
WO 9919354 A1 19990422; WO 9919354 A9 19991202; AU 732079 B2 20010412; AU 9013198 A 19990503; CA 2306453 A1 19990422; CN 1134452 C 20040114; CN 1279689 A 20010110; EP 1023323 A1 20000802; JP 2001519441 A 20011023; KR 20010031120 A 20010416; NZ 504025 A 20030429; SE 9801148 D0 19980331
DOCDB simple family (application)
SE 9801548 W 19980831; AU 9013198 A 19980831; CA 2306453 A 19980831; CN 98811226 A 19980831; EP 98941985 A 19980831; JP 2000515925 A 19980831; KR 20007004011 A 20000414; NZ 50402598 A 19980831; SE 9801148 A 19980331