Global Patent Index - EP 1025105 A1

EP 1025105 A1 2000-08-09 - CONDENSED BENZOTHIOPYRANIC COMPOUNDS

Title (en)

CONDENSED BENZOTHIOPYRANIC COMPOUNDS

Title (de)

KONDENSIERTE BENZOTHIOPYRAN-DERIVATE

Title (fr)

COMPOSES BENZOTHIOPYRANIQUES CONDENSES

Publication

EP 1025105 A1 (EN)

Application

EP 98947544 A

Priority

  • EP 9806052 W
  • GB 9720901 A

Abstract (en)

[origin: WO9916771A1] The use of a compound of formula (I) wherein W is a -CONH-, -SO2- or -CO-; X is -O- or -NR2- in which R2 is C1-C6 alkyl, benzyl, pyridyl or a phenyl ring, the phenyl ring being unsubstituted or substituted by one or two substituents chosen independently from halogen, trifluoromethyl, C1-C6 alkyl, C1-C6 alkoxy, nitro, amino, hydroxy, formylamino, C2-C6 alkanoylamino and C1-C6 alkoxy-carbonyl; each of R and R1 is independently hydrogen, halogen, hydroxy, trifluoromethyl, nitro, amino, phenyl, benzyl, C1-C6 alkyl, C1-C6 alkoxy, C2-C6 alkanoylamino, formylanino or C1-C6 alkoxy-carbonyl; m is zero or an integer of 1 to 6 and Q is C1-C14 alkyl; or m is zero, 1 or 2 and Q is a phenyl ring or an unsaturated pentatomic heteromonocyclic ring containing two or three heteroatoms chosen independently from oxygen, sulphur and nitrogen, wherein the phenyl ring and the heteromonocyclic ring are unsubstituted or substituted by one or two substituents chosen independently from halogen, hydroxy, trifluoromethyl, nitro, amino, phenyl, benzyl, C1-C6 alkyl, C1-C6 alkoxy, C2-C6 alkanoylamino, formylamino and C1-C6 alkoxy-carbonyl; or a pharmaceutically acceptable salt thereof, in the manufacture of a medicament for use as kynurenine-3-hydroxylase inhibitor is disclosed.

IPC 1-7 (main, further and additional classification)

C07D 495/04; A61K 31/38; A61K 31/415

IPC 8 full level (invention and additional information)

A61K 31/38 (2006.01); A61K 31/415 (2006.01); A61P 25/00 (2006.01); A61P 43/00 (2006.01); C07D 495/04 (2006.01); C07D 498/04 (2006.01)

CPC (invention and additional information)

C07D 495/04 (2013.01)

Citation (search report)

See references of WO 9916771A1

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

EPO simple patent family

WO 9916771 A1 19990408; AU 9441598 A 19990423; CA 2302027 A1 19990408; EP 1025105 A1 20000809; GB 9720901 D0 19971203; JP 2001518473 A 20011016

INPADOC legal status


2002-02-13 [18D] DEEMED TO BE WITHDRAWN

- Effective date: 20010626

2001-03-28 [17Q] FIRST EXAMINATION REPORT

- Effective date: 20010213

2000-08-09 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 20000330

2000-08-09 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A1

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

2000-08-09 [AX] REQUEST FOR EXTENSION OF THE EUROPEAN PATENT TO

- Free text: AL PAYMENT 20000330;LT PAYMENT 20000330;LV PAYMENT 20000330;MK PAYMENT 20000330;RO PAYMENT 20000330;SI PAYMENT 20000330