EP 1025127 A1 20000809 - MSH-RECEPTOR SUBTYPE SELECTIVE CYCLIC PEPTIDES
Title (en)
MSH-RECEPTOR SUBTYPE SELECTIVE CYCLIC PEPTIDES
Title (de)
MSH REZEPTOR SUBTYP SELEKTIVE ZYKLISCHE PEPTIDE
Title (fr)
PEPTIDES CYCLIQUES SELECTIFS VIS-A-VIS DE SOUS-TYPES DE RECEPTEURS MSH
Publication
Application
Priority
- SE 9800270 W 19980216
- SE 9700620 A 19970221
Abstract (en)
[origin: WO9837097A1] Cyclic MC-receptor activating and/or blocking peptides of general formula (I) in which LRG is a large aminoacid and L is 26-29 membered linker connecting LRG and Trp are useful for treating conditions related to eating, body weight, motivation, learning, memory, behaviour, inflammation, body temperature, pain perception, blood pressure, heart rate, vascular tone, natriuresis, brain blood flow, nerve growth, placental development, aldosteron synthesis and release, thyroxin release, spermatogenesis, ovarian weight, prolacting and FSH secretion, uterine bleeding in women, sebum and pheromone secretion, blood glucose levels, intrauterine foetal growth, as well as other events related to parturition, and to afford neuroprotection. The novel peptides can also be labeled and be incorporated into pharmaceutical compositions.
IPC 1-7
IPC 8 full level
C07K 14/68 (2006.01); A61K 38/00 (2006.01)
CPC (source: EP)
C07K 14/68 (2013.01); A61K 38/00 (2013.01)
Citation (search report)
See references of WO 9837097A1
Designated contracting state (EPC)
AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9837097 A1 19980827; AU 6127498 A 19980909; EP 1025127 A1 20000809; SE 9700620 D0 19970221
DOCDB simple family (application)
SE 9800270 W 19980216; AU 6127498 A 19980216; EP 98905907 A 19980216; SE 9700620 A 19970221