Global Patent Index - EP 1025251 A1

EP 1025251 A1 2000-08-09 - AMPLIFIABLE ADENO-ASSOCIATED VIRUS (AAV) PACKAGING CASSETTES FOR THE PRODUCTION OF RECOMBINANT AAV VECTORS

Title (en)

AMPLIFIABLE ADENO-ASSOCIATED VIRUS (AAV) PACKAGING CASSETTES FOR THE PRODUCTION OF RECOMBINANT AAV VECTORS

Title (de)

VERMEHRBARE 'VERPACKUNGS-KASSETTEN' DES ADENO-ASSOZIIERTEN VIRUS (AAV) FÜR DIE PRODUKTION VON REKOMBINANTEN AAV-VEKTOREN

Title (fr)

CASSETTES D'ENCAPSIDATION DE VIRUS ADENO-ASSOCIE (AAV) AMPLIFIABLE POUR LA PRODUCTION DE VECTEURS DE AAV RECOMBINES

Publication

EP 1025251 A1 (EN)

Application

EP 98953640 A

Priority

  • US 9821938 W
  • US 95523297 A

Abstract (en)

[origin: WO9920779A1] High-efficiency AAV packaging constructs and methods for their use are provided in the present invention. These high-efficiency packaging constructs comprise an activating element (such as the P1 sequence located within the AAV S1 integration site of human chromosome 19) amplifiably linked to one or more AAV packaging genes. The constructs may be either integrated into a mammalian cell genome or maintained episomally. Use of the high-efficiency AAV packaging vectors of the invention provides for controlled amplifiable production of rAAV vector constructs.

IPC 1-7 (main, further and additional classification)

C12N 15/86; C12N 5/10; C12N 7/01; C12N 15/35; C12N 15/69

IPC 8 full level (invention and additional information)

C12N 15/09 (2006.01); C12N 7/00 (2006.01); C12N 7/01 (2006.01); C12N 15/864 (2006.01)

CPC (invention and additional information)

C12N 15/86 (2013.01); C12N 7/00 (2013.01); C12N 2750/14143 (2013.01); C12N 2750/14152 (2013.01)

Citation (search report)

See references of WO 9920779A1

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

EPO simple patent family

WO 9920779 A1 19990429; AU 1096799 A 19990510; AU 758541 B2 20030327; CA 2308008 A1 19990429; EP 1025251 A1 20000809; JP 2001520051 A 20011030

INPADOC legal status


2006-08-23 [18D] DEEMED TO BE WITHDRAWN

- Effective date: 20060228

2002-03-20 [17Q] FIRST EXAMINATION REPORT

- Effective date: 20020205

2000-08-09 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 20000515

2000-08-09 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A1

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE