EP 1027029 A1 20000816 - IMPROVED PERSONAL CARE FORMULATIONS
Title (en)
IMPROVED PERSONAL CARE FORMULATIONS
Title (de)
VERBESSERTE KÖRPERPFLEGE FORMULIERUNGEN
Title (fr)
FORMULATIONS AMELIOREES DE SOINS PERSONNELS
Publication
Application
Priority
- IL 9800504 W 19981018
- IL 12208497 A 19971031
Abstract (en)
[origin: WO9922703A1] Personal care and hygiene formulations for topical application to mucosal surfaces. These formulations include an amphiphilic lipid carrier in the form of a colloidal composition which can include a micellar aggregate or mixed micelles dispersed in a continuous aqueous phase, or an emulsion of lipid droplets suspended in a continuous aqueous phase, and an active agent which is an anti-microbial agent. The lipid carrier has high adhesiveness to mucous membranes such as the soft tissues of the oral cavity. The lipid carrier also has a high load capacity for the active agent to be carried to these tissues. These formulations have the desirable properties of carrying a large amount of active agent for controlled and prolonged release thereof at the desired site, such as mucous membrane surfaces and surrounding tissue. Accordingly, the present invention provides a formulation for oral or topical application including an anti-microbial agent and a lipid. The agent is held by the carrier through a hydrophobic interaction and is released from the carrier in a controlled manner over a prolonged period of time. The lipid is also characterized by having a high adhesive capability towards mucous membrane surfaces. The lipid and the agent are preferably present in a ratio in a range of from about 1:10 to about 10:1, more preferably from about 1:5 to about 5:1, and most preferably from about 1:3 to about 3:1 in the formulation.
IPC 1-7
IPC 8 full level
A61K 8/00 (2006.01); A61K 8/04 (2006.01); A61K 8/14 (2006.01); A61K 8/34 (2006.01); A61K 8/37 (2006.01); A61K 8/40 (2006.01); A61K 8/43 (2006.01); A61K 8/46 (2006.01); A61K 8/49 (2006.01); A61K 8/55 (2006.01); A61K 8/84 (2006.01); A61K 8/86 (2006.01); A61K 8/97 (2006.01); A61K 9/00 (2006.01); A61K 9/107 (2006.01); A61K 9/113 (2006.01); A61K 9/127 (2006.01); A61K 31/07 (2006.01); A61K 31/085 (2006.01); A61K 31/122 (2006.01); A61K 31/13 (2006.01); A61K 31/14 (2006.01); A61K 31/155 (2006.01); A61K 31/165 (2006.01); A61K 31/167 (2006.01); A61K 31/192 (2006.01); A61K 31/205 (2006.01); A61K 31/27 (2006.01); A61K 31/35 (2006.01); A61K 31/355 (2006.01); A61K 31/375 (2006.01); A61K 31/4164 (2006.01); A61K 31/496 (2006.01); A61K 31/616 (2006.01); A61K 31/7072 (2006.01); A61Q 11/00 (2006.01)
CPC (source: EP KR)
A61K 8/0291 (2013.01 - EP); A61K 8/04 (2013.01 - KR); A61K 8/347 (2013.01 - EP); A61K 8/43 (2013.01 - EP); A61K 8/553 (2013.01 - EP); A61K 8/84 (2013.01 - EP); A61K 9/0053 (2013.01 - EP); A61K 9/1075 (2013.01 - EP); A61K 9/127 (2013.01 - EP); A61K 31/085 (2013.01 - EP); A61K 31/155 (2013.01 - EP); A61Q 11/00 (2013.01 - EP); B82Y 5/00 (2013.01 - EP); A61K 2800/413 (2013.01 - EP)
Designated contracting state (EPC)
AT DE FR GB IT NL
DOCDB simple family (publication)
WO 9922703 A1 19990514; AU 758188 B2 20030320; AU 9558798 A 19990524; CA 2307886 A1 19990514; CN 1283983 A 20010214; EP 1027029 A1 20000816; EP 1027029 A4 20050907; IL 122084 A0 19980310; IL 122084 A 19990922; JP 2001521882 A 20011113; KR 20010031621 A 20010416
DOCDB simple family (application)
IL 9800504 W 19981018; AU 9558798 A 19981018; CA 2307886 A 19981018; CN 98811388 A 19981018; EP 98949227 A 19981018; IL 12208497 A 19971031; JP 2000518642 A 19981018; KR 20007004673 A 20000429