EP 1027049 A4 20010905 - INTRANASAL FORMULATION CONTAINING SCOPOLAMINE AND METHOD OF TREATING MOTION SICKNESS
Title (en)
INTRANASAL FORMULATION CONTAINING SCOPOLAMINE AND METHOD OF TREATING MOTION SICKNESS
Title (de)
INTRANASALE FORMULIERUNG ENTHALTEND SCOPOLAMIN UND VERFAHREN ZUR BEHANDLUNG VON REISEKRANKHEIT
Title (fr)
FORMULATION INTRANASALE CONTENANT DE LA SCOPOLAMINE ET METHODE DE TRAITEMENT DU MAL DES TRANSPORTS
Publication
Application
Priority
- US 9818953 W 19980911
- US 5865197 P 19970911
Abstract (en)
[origin: WO9912544A1] The present invention relates to pharmaceutical formulations containing scopolamine. More particularly, the invention relates to an intranasal gel formulation including scopolamine hydrobromide in a pharmaceutically acceptable carrier, most preferably an intranasal gel, at a pH at or below about 4.0, preferably at or below about 3.5, and a salt concentration below about 200 mM, with the gel solution incorporating polyvinylalcohol as a gelling agent. The intranasal formulations are particularly useful for preventing and/or treating nausea and/or vomiting associated with, for example, motion sickness.
IPC 1-7
IPC 8 full level
A61K 9/00 (2006.01); A61K 31/439 (2006.01); A61K 31/46 (2006.01); A61K 47/32 (2006.01); A61P 1/08 (2006.01)
CPC (source: EP)
A61K 9/0043 (2013.01); A61K 31/46 (2013.01); A61K 47/32 (2013.01); A61P 1/00 (2017.12); A61P 1/08 (2017.12)
Citation (search report)
- [A] EP 0131315 A2 19850116 - ANGELI INST SPA [IT]
- [A] PUTCHA LAKSHIMI ET AL: "Bioavailability of intranasal scopolamine in normal subjects.", JOURNAL OF PHARMACEUTICAL SCIENCES, vol. 85, no. 8, 1996, pages 899 - 902, XP002171369, ISSN: 0022-3549
- See references of WO 9912544A1
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9912544 A1 19990318; AU 742878 B2 20020117; AU 9385098 A 19990329; CA 2303132 A1 19990318; CA 2303132 C 20020709; EP 1027049 A1 20000816; EP 1027049 A4 20010905; JP 2002516815 A 20020611
DOCDB simple family (application)
US 9818953 W 19980911; AU 9385098 A 19980911; CA 2303132 A 19980911; EP 98946945 A 19980911; JP 2000510441 A 19980911