Global Patent Index - EP 1027071 A2

EP 1027071 A2 2000-08-16 - ENCAPSULATED IMMUNOMODULATORS USEFUL AS VACCINE ADJUVANTS

Title (en)

ENCAPSULATED IMMUNOMODULATORS USEFUL AS VACCINE ADJUVANTS

Title (de)

EINGEKAPSELTE IMMUNMODULATOREN ALS IMPFSTOFFADJUVANTIEN

Title (fr)

IMMUNOMODULATEURS ENCAPSULES UTILISES COMME ADJUVANTS DE VACCINS

Publication

EP 1027071 A2 (EN)

Application

EP 98955231 A

Priority

  • US 9823313 W
  • US 96240797 A

Abstract (en)

[origin: WO9922763A2] The present invention concerns compositions comprising an encapsulated immunomodulator, such as cytokines and lymphokines, that is useful as an adjuvant for stimulating an immune response when administered to a human or animal. For example, a lymphokine such as IL-1 alpha or IL-1 beta can be used as an immunomodulator encapsulated in a matrix according to the invention. The encapsulated composition can include a vaccine antigen, such as whole inactivated or attenuated virus, recombinant or synthetic peptides, and other antigenic materials. The encapsulation matrix can be natural or synthetic. The present invention also pertains to the use of an encapsulated immunomodulator in a human or animal as an adjuvant to increase immune responses to an antigen or other material to which an immune response is desired.

IPC 1-7 (main, further and additional classification)

A61K 39/39; A61K 9/127; A61K 38/20; A61K 39/00; A61K 39/145

IPC 8 full level (invention and additional information)

C12N 7/00 (2006.01); A61K 9/00 (2006.01); A61K 9/127 (2006.01); A61K 38/00 (2006.01); A61K 38/20 (2006.01); A61K 39/00 (2006.01); A61K 39/145 (2006.01); A61K 39/39 (2006.01); A61K 45/00 (2006.01); A61P 31/12 (2006.01); C07K 14/54 (2006.01); C07K 14/545 (2006.01)

CPC (invention and additional information)

A61K 39/39 (2013.01); A61K 9/127 (2013.01); A61K 38/2006 (2013.01); A61K 2039/55527 (2013.01); A61K 2039/55533 (2013.01); A61K 2039/55538 (2013.01); A61K 2039/55555 (2013.01)

Citation (search report)

See references of WO 9922763A3

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

EPO simple patent family

WO 9922763 A2 19990514; WO 9922763 A3 19990805; AU 1208499 A 19990524; CA 2307541 A1 19990514; EP 1027071 A2 20000816; IL 135480 D0 20010520; JP 2001521908 A 20011113

INPADOC legal status


2006-03-15 [18D] DEEMED TO BE WITHDRAWN

- Effective date: 20050728

2004-08-11 [17Q] FIRST EXAMINATION REPORT

- Effective date: 20040625

2000-08-16 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 20000502

2000-08-16 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A2

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE