Global Patent Index - EP 1027073 A2

EP 1027073 A2 2000-08-16 - ENHANCED EFFECTS FOR HAPTEN CONJUGATED THERAPEUTICS

Title (en)

ENHANCED EFFECTS FOR HAPTEN CONJUGATED THERAPEUTICS

Title (de)

VERSTÄRKTER EFFEKT FÜR HAPTEN-KONJUGIERTEN HAPTENEN

Title (fr)

EFFETS RENFORCES POUR THERAPEUTIQUE ASSOCIEE A L'HAPTENE

Publication

EP 1027073 A2 (EN)

Application

EP 97949336 A

Priority

  • US 9718475 W
  • US 75267196 A

Abstract (en)

[origin: WO9822141A2] Novel methods for enhancing the effective in vivo half life of therapeutic compounds in mammals are provided. Specifically, therapeutic compounds are conjugated to a haptenic moiety. Upon administration to the mammalian subject, the therapeutic compound/hapten conjugates are bound by circulating antibodies directed specifically against the haptenic moiety of the conjugate, thereby resulting in a stabilization of the conjugate in the vascular system and an effective increase in the in vivo half life of the therapeutic compound.

IPC 1-7 (main, further and additional classification)

A61K 47/48

IPC 8 full level (invention and additional information)

A61K 47/48 (2006.01)

CPC (invention and additional information)

A61K 47/4833 (2013.01)

Citation (search report)

See references of WO 9822141A3

Designated contracting state (EPC)

AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

EPO simple patent family

WO 9822141 A2 19980528; WO 9822141 A3 19990107; AU 7298398 A 19980610; EP 1027073 A2 20000816

INPADOC legal status


2003-10-22 [18D] DEEMED TO BE WITHDRAWN

- Effective date: 20030418

2002-11-20 [17Q] FIRST EXAMINATION REPORT

- Effective date: 20021007

2000-08-16 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 19990610

2000-08-16 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A2

- Designated State(s): AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE