EP 1027347 A2 20000816 - 3-AMINOALKYLAMINO-2H-1,4-BENZOXA(THIA-)ZINES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
Title (en)
3-AMINOALKYLAMINO-2H-1,4-BENZOXA(THIA-)ZINES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
Title (de)
3-AMINOALKYLAMINO-2H-1,4-BENZOXA(THIA-)ZINEN UND DIESE ENTHALTENDE PHARMAZEUTISCHE ZUSAMMENSTELLUNGEN
Title (fr)
3-AMINOALKYLAMINO- 2H-1,4-BENZOXAZINES ET 3-AMINOALKYLAMINO- 2H-1,4-BENZOTHIAZINES CONSTITUANT DES LIGANDS SPECIFIQUES D'UN SOUS-TYPE DE RECEPTEUR DE LA DOPAMINE
Publication
Application
Priority
- US 9822936 W 19981028
- US 96202297 A 19971031
Abstract (en)
[origin: WO9923092A2] Disclosed are compounds of formula (I) or the pharmaceutically acceptable acid addition salts thereof, wherein: Ar represents aryl or heteroaryl; R1 and R2 are the same or different and represent organic or inorganic substituents; R5 is hydrogen or C1-C6 alkyl; W represents CH or nitrogen; X is oxygen or sulfur; and A represents an alkylene group, which compounds bind selectively with high affinity to the dopamine D4 receptor subtype and are therefore of use in treatment of various neuropsychological disorders.
IPC 1-7
IPC 8 full level
C07D 279/16 (2006.01); A61K 31/538 (2006.01); A61K 31/5415 (2006.01); A61P 21/02 (2006.01); A61P 25/16 (2006.01); A61P 25/18 (2006.01); A61P 25/24 (2006.01); A61P 25/28 (2006.01); C07D 265/36 (2006.01); C07D 413/12 (2006.01); C07D 417/12 (2006.01)
CPC (source: EP)
A61P 21/02 (2017.12); A61P 25/16 (2017.12); A61P 25/18 (2017.12); A61P 25/24 (2017.12); A61P 25/28 (2017.12); C07D 265/36 (2013.01); C07D 413/12 (2013.01); C07D 417/12 (2013.01)
Citation (search report)
See references of WO 9923092A2
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9923092 A2 19990514; WO 9923092 A3 19990805; AU 1286399 A 19990524; CA 2307905 A1 19990514; EP 1027347 A2 20000816; JP 2001521935 A 20011113
DOCDB simple family (application)
US 9822936 W 19981028; AU 1286399 A 19981028; CA 2307905 A 19981028; EP 98956310 A 19981028; JP 2000518963 A 19981028