Global Patent Index - EP 1027347 A2

EP 1027347 A2 2000-08-16 - 3-AMINOALKYLAMINO-2H-1,4-BENZOXA(THIA-)ZINES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

Title (en)

3-AMINOALKYLAMINO-2H-1,4-BENZOXA(THIA-)ZINES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

Title (de)

3-AMINOALKYLAMINO-2H-1,4-BENZOXA(THIA-)ZINEN UND DIESE ENTHALTENDE PHARMAZEUTISCHE ZUSAMMENSTELLUNGEN

Title (fr)

3-AMINOALKYLAMINO- 2H-1,4-BENZOXAZINES ET 3-AMINOALKYLAMINO- 2H-1,4-BENZOTHIAZINES CONSTITUANT DES LIGANDS SPECIFIQUES D'UN SOUS-TYPE DE RECEPTEUR DE LA DOPAMINE

Publication

EP 1027347 A2 (EN)

Application

EP 98956310 A

Priority

  • US 9822936 W
  • US 96202297 A

Abstract (en)

[origin: WO9923092A2] Disclosed are compounds of formula (I) or the pharmaceutically acceptable acid addition salts thereof, wherein: Ar represents aryl or heteroaryl; R1 and R2 are the same or different and represent organic or inorganic substituents; R5 is hydrogen or C1-C6 alkyl; W represents CH or nitrogen; X is oxygen or sulfur; and A represents an alkylene group, which compounds bind selectively with high affinity to the dopamine D4 receptor subtype and are therefore of use in treatment of various neuropsychological disorders.

IPC 1-7 (main, further and additional classification)

C07D 403/00

IPC 8 full level (invention and additional information)

C07D 279/16 (2006.01); A61K 31/538 (2006.01); A61K 31/5415 (2006.01); A61P 21/02 (2006.01); A61P 25/16 (2006.01); A61P 25/18 (2006.01); A61P 25/24 (2006.01); A61P 25/28 (2006.01); C07D 265/36 (2006.01); C07D 413/12 (2006.01); C07D 417/12 (2006.01)

CPC (invention and additional information)

C07D 413/12 (2013.01); C07D 265/36 (2013.01); C07D 417/12 (2013.01)

Citation (search report)

See references of WO 9923092A3

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

EPO simple patent family

WO 9923092 A2 19990514; WO 9923092 A3 19990805; AU 1286399 A 19990524; CA 2307905 A1 19990514; EP 1027347 A2 20000816; JP 2001521935 A 20011113

INPADOC legal status


2000-10-25 [18W] WITHDRAWN

- Date of withdrawal: 20000828

2000-08-16 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 20000523

2000-08-16 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A2

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

2000-08-16 [AX] REQUEST FOR EXTENSION OF THE EUROPEAN PATENT TO

- Free text: AL PAYMENT 20000523;LT PAYMENT 20000523;LV PAYMENT 20000523;MK PAYMENT 20000523;RO PAYMENT 20000523;SI PAYMENT 20000523