Global patent index - EP 1027425 A1

EP 1027425 A1 2000-08-16 - A METHOD OF IMPROVED MIXING IN ROLLER BOTTLES

Title (en)

A METHOD OF IMPROVED MIXING IN ROLLER BOTTLES

Title (de)

METHODE FÜR VERBESSERTES MISCHEN IN ROLLFLASCHEN

Title (fr)

PROCEDE DE MELANGE AMELIORE DANS DES BOUTEILLES POUR AGITATEUR ROTATIF

Publication

EP 1027425 A1 (EN)

Application

EP 98955135 A

Priority

  • GB 9727128 A
  • US 9822729 W
  • US 6385497 P
  • US 6737197 P

Abstract (en)

[origin: WO9923204A1] A method for enhancing the mixing of materials in roller bottle by the introduction of controlled axial and cross-sectional flow perturbations is disclosed. The effectiveness of the method is demonstrated by achieving higher efficiency in cell culturing and virus propagation in roller bottles by introducing controlled flow perturbations during the process.

IPC 1-7 (main, further and additional classification)

C12N 5/02

IPC 8 full level (invention and additional information)

C12M 3/04 (2006.01); C12N 5/02 (2006.01)

CPC (invention and additional information)

C12M 27/12 (2013.01); C12M 27/16 (2013.01)

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU NL PT SE

EPO simple patent family

WO 9923204 A1 19990514; AU 1201599 A 19990524; AU 737705 B2 20010830; CA 2308111 A1 19990514; CA 2308111 C 20101221; EP 1027425 A1 20000816; EP 1027425 A4 20060419; JP 2001521736 A 20011113

INPADOC legal status

2013-10-23 [18D] DEEMED TO BE WITHDRAWN

- Ref Legal Event Code: 18D

- Effective date: 20130503

2010-03-10 [RAP1] TRANSFER OF RIGHTS OF AN EP PUBLISHED APPLICATION

- Owner name: MERCK SHARP & DOHME CORP.

- Ref Legal Event Code: RAP1

2010-03-10 [RAP1] TRANSFER OF RIGHTS OF AN EP PUBLISHED APPLICATION

- Owner name: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY

- Ref Legal Event Code: RAP1

2006-10-25 [17Q] FIRST EXAMINATION REPORT

- Ref Legal Event Code: 17Q

- Effective date: 20060920

2006-04-19 [A4] SUPPLEMENTARY SEARCH REPORT

- Ref Legal Event Code: A4

- Effective date: 20060306

2000-08-16 [17P] REQUEST FOR EXAMINATION FILED

- Ref Legal Event Code: 17P

- Effective date: 20000531

2000-08-16 [AK] DESIGNATED CONTRACTING STATES:

- Ref Legal Event Code: AK

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU NL PT SE

2000-08-16 [AX] REQUEST FOR EXTENSION OF THE EUROPEAN PATENT TO

- Ref Legal Event Code: AX

- Free Format Text: AL PAYMENT 20000531;LT PAYMENT 20000531;LV PAYMENT 20000531;MK PAYMENT 20000531;RO PAYMENT 20000531;SI PAYMENT 20000531