Global Patent Index - EP 1028956 A1

EP 1028956 A1 2000-08-23 - IMIDAZOYLALKYL SUBSTITUTED WITH A FIVE, SIX OR SEVEN MEMBERED HETEROCYCLIC RING CONTAINING ONE NITROGEN ATOM

Title (en)

IMIDAZOYLALKYL SUBSTITUTED WITH A FIVE, SIX OR SEVEN MEMBERED HETEROCYCLIC RING CONTAINING ONE NITROGEN ATOM

Title (de)

MIT EINEM N-ATOM ENTHALTENDE 5, 6 ODER 7-GLIEDRIGEN HETEROZYCLISCHE RING SUBSTITUIERTE IMIDAZOLALKYL DERIVATE

Title (fr)

IMIDAZOYLALKYLE SUBSTITUE PAR UN NOYAU HETEROCYCLIQUE A CINQ, SIX OU SEPT CHAINONS CONTENANT UN ATOME D'AZOTE

Publication

EP 1028956 A1 (EN)

Application

EP 98956443 A

Priority

  • US 9823224 W
  • US 96575497 A

Abstract (en)

[origin: WO9924421A1] Disclosed are compounds of Formula (I) or pharmaceutically acceptable salts or solvates thereof. Also disclosed are pharmaceutical compositions comprising a pharmaceutically acceptable carrier and an effective amount of a Compound of Formula (I). Further disclosed is a method of treating allergy (for example asthma), inflammation, hypotension, raised intraocular pressure (such as glaucoma) i.e., a method of lowering intraocular pressure, sleeping disorders, states of hyper and hypo motility and acidic secretion of the gastrointestinal tract, hypo and hyperactivity of the central nervous system (for example, agitation and depression) and other CNS disorders (such as Alzheimer's, Schizophrenia, obesity and migraine) comprising administering an effective amount of a compound of Formula (I) to a patient in need of such treatment. Also disclosed are methods for treatment of upper airway allergic responses comprising administering a compound, or salt or solvate thereof, of Formula (I) in combination or admixture with a histamine H1 receptor antagonist.

IPC 1-7 (main, further and additional classification)

C07D 401/06; A61K 31/415; A61K 31/445; C07D 403/06

IPC 8 full level (invention and additional information)

A61K 31/4178 (2006.01); A61K 31/4427 (2006.01); A61K 31/445 (2006.01); A61K 31/454 (2006.01); A61K 31/495 (2006.01); A61P 1/00 (2006.01); A61P 3/04 (2006.01); A61P 9/00 (2006.01); A61P 9/02 (2006.01); A61P 25/00 (2006.01); A61P 25/06 (2006.01); A61P 25/18 (2006.01); A61P 25/20 (2006.01); A61P 25/28 (2006.01); A61P 27/06 (2006.01); A61P 37/08 (2006.01); C07D 401/06 (2006.01); C07D 403/06 (2006.01)

CPC (invention and additional information)

C07D 401/06 (2013.01); A61K 31/445 (2013.01); A61K 31/495 (2013.01); C07D 403/06 (2013.01)

Combination set (CPC)

  1. A61K 31/495 + A61K 31/445
  2. A61K 31/495 + A61K 31/415
  3. A61K 31/445 + A61K 31/445
  4. A61K 31/445 + A61K 31/415
  5. A61K 31/445 + A61K 2300/00
  6. A61K 31/495 + A61K 2300/00

Citation (search report)

See references of WO 9924421A1

Designated contracting state (EPC)

AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE

EPO simple patent family

WO 9924421 A1 19990520; WO 9924421 A8 19990826; AR 016671 A1 20010725; AU 1296799 A 19990531; CA 2309609 A1 19990520; CN 1285828 A 20010228; EP 1028956 A1 20000823; HU 0102662 A2 20011228; HU 0102662 A3 20030128; IL 135727 D0 20010520; JP 2001522845 A 20011120; PE 130699 A1 19991216; ZA 9810186 B 19990506

INPADOC legal status


2007-06-15 [REG HK WD] APPLICATIONS WITHDRAWN, DEEMED TO BE WITHDRAWN, OR REFUSED AFTER PUBLICATION IN HONG KONG

- Document: HK 1025970

2002-03-13 [18W] WITHDRAWN

- Date of withdrawal: 20020111

2001-02-14 [17Q] FIRST EXAMINATION REPORT

- Effective date: 20010102

2000-08-23 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 20000510

2000-08-23 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A1

- Designated State(s): AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE

2000-08-23 [AX] REQUEST FOR EXTENSION OF THE EUROPEAN PATENT TO

- Free text: LT PAYMENT 20000510;LV PAYMENT 20000510;RO PAYMENT 20000510