EP 1028969 A2 20000823 - NEW SOPHOROSELIPIDS, METHOD FOR THEIR PRODUCTION AND USE
Title (en)
NEW SOPHOROSELIPIDS, METHOD FOR THEIR PRODUCTION AND USE
Title (de)
NEUARTIGE SOPHOROSELIPIDE, VERFAHREN ZU DEREN HERSTELLUNG UND VERWENDUNG
Title (fr)
NOUVEAUX SOPHOROSELIPIDES, LEUR PROCEDE DE FABRICATION ET LEUR UTILISATION
Publication
Application
Priority
- DE 19749413 A 19971107
- EP 9806590 W 19981017
Abstract (en)
[origin: DE19749413A1] The invention relates to sophoroselipids of formula (I) wherein R<4> represents H, -CH2CH3, -CH2CH2CH3, n is an integer number from 2 to 27, R<1> and R<2> represent, independently from each other, H or a group of formula (II), and R<3> represents H or -OH. The invention also relates to a method for producing sophoroselipids of formula (I) wherein R<1>, R<2>, R<3> and n have the aforementioned meanings and R<4> represents -CH3, -CH2CH3 or -CH2CH2CH3. According to this method, a yeast capable of secreting a sophoroselipid in the form of a lactone in the culture excess, is fermented in a culture medium containing a glycerin, a succinate, a mono-, di- and/or tri-saccharide and a lipid precursor, said sophoroselipid being then isolated from the culture solution. The inventive method is characterised in that the lipid precursor contains one or more 3-alkanols, 4-alkanols or an alkanone with a chain length from 6 to 30 carbon atoms or mixtures of said alkanols/alkanone. Furthermore, according to a variant of the aforementioned method for producing sophoroselipids of formula (I), wherein R<1>, R<2>, R<3> and n have the meanings aforementioned and R<4> represents -CH3, -CH2CH3 or -CH2CH2CH3, the culture medium is maintained during fermentation under a reduced oxygen concentration. The new sophoroselipids may be used, e.g., as surfactants, cosmetics, disinfecting agents or pharmaceutical products.
IPC 1-7
IPC 8 full level
A01N 1/00 (2006.01); A01N 43/16 (2006.01); A61K 8/06 (2006.01); A61K 8/60 (2006.01); A61K 8/73 (2006.01); A61K 31/70 (2006.01); A61K 47/26 (2006.01); A61L 2/16 (2006.01); A61Q 19/00 (2006.01); C07G 3/00 (2006.01); C07H 13/06 (2006.01); C07H 15/04 (2006.01); C07H 15/207 (2006.01); C11D 1/66 (2006.01); C11D 3/22 (2006.01); C12P 19/44 (2006.01); C12P 19/46 (2006.01); C12R 1/72 (2006.01)
CPC (source: EP US)
A01N 43/16 (2013.01 - EP US); A61K 8/602 (2013.01 - EP US); A61Q 19/00 (2013.01 - EP US); C07H 15/04 (2013.01 - EP US); C11D 1/667 (2013.01 - EP US); C12P 19/46 (2013.01 - EP US); A61K 2800/85 (2013.01 - EP US)
Citation (search report)
See references of WO 9924448A2
Designated contracting state (EPC)
AT BE CH DE DK ES FI FR GB IT LI NL SE
DOCDB simple family (publication)
DE 19749413 A1 19990512; EP 1028969 A2 20000823; JP 2001522597 A 20011120; US 6433152 B1 20020813; WO 9924448 A2 19990520; WO 9924448 A3 19990819
DOCDB simple family (application)
DE 19749413 A 19971107; EP 9806590 W 19981017; EP 98955474 A 19981017; JP 2000520456 A 19981017; US 53076900 A 20000703