Global patent index - EP 1028969 A2

EP 1028969 A2 2000-08-23 - NEW SOPHOROSELIPIDS, METHOD FOR THEIR PRODUCTION AND USE

Title (en)

NEW SOPHOROSELIPIDS, METHOD FOR THEIR PRODUCTION AND USE

Title (de)

NEUARTIGE SOPHOROSELIPIDE, VERFAHREN ZU DEREN HERSTELLUNG UND VERWENDUNG

Title (fr)

NOUVEAUX SOPHOROSELIPIDES, LEUR PROCEDE DE FABRICATION ET LEUR UTILISATION

Publication

EP 1028969 A2 (DE)

Application

EP 98955474 A

Priority

  • DE 19749413 A
  • EP 9806590 W

Abstract (en)

[origin: DE19749413A1] The invention relates to sophoroselipids of formula (I) wherein R<4> represents H, -CH2CH3, -CH2CH2CH3, n is an integer number from 2 to 27, R<1> and R<2> represent, independently from each other, H or a group of formula (II), and R<3> represents H or -OH. The invention also relates to a method for producing sophoroselipids of formula (I) wherein R<1>, R<2>, R<3> and n have the aforementioned meanings and R<4> represents -CH3, -CH2CH3 or -CH2CH2CH3. According to this method, a yeast capable of secreting a sophoroselipid in the form of a lactone in the culture excess, is fermented in a culture medium containing a glycerin, a succinate, a mono-, di- and/or tri-saccharide and a lipid precursor, said sophoroselipid being then isolated from the culture solution. The inventive method is characterised in that the lipid precursor contains one or more 3-alkanols, 4-alkanols or an alkanone with a chain length from 6 to 30 carbon atoms or mixtures of said alkanols/alkanone. Furthermore, according to a variant of the aforementioned method for producing sophoroselipids of formula (I), wherein R<1>, R<2>, R<3> and n have the meanings aforementioned and R<4> represents -CH3, -CH2CH3 or -CH2CH2CH3, the culture medium is maintained during fermentation under a reduced oxygen concentration. The new sophoroselipids may be used, e.g., as surfactants, cosmetics, disinfecting agents or pharmaceutical products.

IPC 1-7 (main, further and additional classification)

C07H 15/00

IPC 8 full level (invention and additional information)

C12P 19/44 (2006.01); A01N 1/00 (2006.01); A01N 43/16 (2006.01); A61K 8/06 (2006.01); A61K 8/60 (2006.01); A61K 8/73 (2006.01); A61K 31/70 (2006.01); A61K 47/26 (2006.01); A61L 2/16 (2006.01); A61Q 19/00 (2006.01); C07G 3/00 (2006.01); C07H 13/06 (2006.01); C07H 15/04 (2006.01); C07H 15/207 (2006.01); C11D 1/66 (2006.01); C11D 3/22 (2006.01); C12P 19/46 (2006.01); C12R 1/72 (2006.01)

CPC (invention and additional information)

C11D 1/667 (2013.01); A01N 43/16 (2013.01); A61K 8/602 (2013.01); A61Q 19/00 (2013.01); C07H 15/04 (2013.01); C12P 19/46 (2013.01); A61K 2800/85 (2013.01)

Citation (search report)

See references of WO 9924448A3

Designated contracting state (EPC)

AT BE CH DE DK ES FI FR GB IT LI NL SE

EPO simple patent family

DE 19749413 A1 19990512; EP 1028969 A2 20000823; JP 2001522597 A 20011120; US 6433152 B1 20020813; WO 9924448 A2 19990520; WO 9924448 A3 19990819

INPADOC legal status

2003-11-05 [18W] WITHDRAWN

- Ref Legal Event Code: 18W

- Effective date: 20030913

2002-06-19 [17Q] FIRST EXAMINATION REPORT

- Ref Legal Event Code: 17Q

- Effective date: 20020503

2000-08-23 [17P] REQUEST FOR EXAMINATION FILED

- Ref Legal Event Code: 17P

- Effective date: 20000607

2000-08-23 [AK] DESIGNATED CONTRACTING STATES:

- Ref Legal Event Code: AK

- Designated State(s): AT BE CH DE DK ES FI FR GB IT LI NL SE