Global Patent Index - EP 1028979 A1

EP 1028979 A1 2000-08-23 - VARIABLE REGION FUSION PEPTIDES THAT FORM EFFECTOR COMPLEXES IN THE PRESENCE OF ANTIGEN

Title (en)

VARIABLE REGION FUSION PEPTIDES THAT FORM EFFECTOR COMPLEXES IN THE PRESENCE OF ANTIGEN

Title (de)

VERÄNDERLICHE REGION-FUSIONSPEPTIDE DIE EFFEKTORKOMPLEXE BILDEN IN DER GEGENWART EINES ANTIGENS

Title (fr)

PEPTIDES DE FUSION DE REGION VARIABLE QUI FORMENT DES COMPLEXES EFFECTEURS EN PRESENCE D'ANTIGENES

Publication

EP 1028979 A1 (EN)

Application

EP 98948515 A

Priority

  • US 9820017 W
  • US 6571997 P

Abstract (en)

[origin: WO9925739A1] The fusion polypeptides of this invention contain a variable region sequence linked to an effector sequence. The polypeptides do not form stable complexes in solution, except in the presence of an antigen. Upon contacting with the antigen, the two variable region sequences bind together, which in turn drives the effector sequences into juxtaposition. Complementation of one effector sequence with the other provides an effector function, such as enzyme activation, which has a number of therapeutic or diagnostic applications.

IPC 1-7 (main, further and additional classification)

C07K 19/00; C12N 9/00; G01N 33/53

IPC 8 full level (invention and additional information)

G01N 33/53 (2006.01); C07K 16/40 (2006.01); C07K 19/00 (2006.01); C12N 9/00 (2006.01); C12N 9/04 (2006.01); C12N 15/09 (2006.01)

CPC (invention and additional information)

C12N 9/0006 (2013.01); C07K 16/40 (2013.01); C07K 19/00 (2013.01); C07K 2319/00 (2013.01)

Citation (search report)

See references of WO 9925739A1

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU NL PT SE

EPO simple patent family

WO 9925739 A1 19990527; CA 2309763 A1 19990527; EP 1028979 A1 20000823; JP 2002502585 A 20020129

INPADOC legal status


2006-08-23 [18D] DEEMED TO BE WITHDRAWN

- Effective date: 20060111

2000-08-23 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 20000609

2000-08-23 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A1

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU NL PT SE