Global patent index - EP 1029061 A2

EP 1029061 A2 2000-08-23 - LYSOZYM-ANALOGOUS PROTEINS AND PEPTIDE HAVING AN ANTI-MICROBIAL ACTIVITY, PRODUCTION OF THE SAME AND USE THEREOF

Title (en)

LYSOZYM-ANALOGOUS PROTEINS AND PEPTIDE HAVING AN ANTI-MICROBIAL ACTIVITY, PRODUCTION OF THE SAME AND USE THEREOF

Title (de)

LYSOZYM-ANALOGE PROTEINE UND PEPTIDE MIT ANTIMIKROBIELLER WIRKUNG, IHRE HERSTELLUNG UND IHRE VERWENDUNG

Title (fr)

PROTEINES ET PEPTIDES ANALOGUES AU LYSOZYME ET A ACTION ANTIMICROBIENNE, LEUR PRODUCTION ET LEUR UTILISATION

Publication

EP 1029061 A2 (DE)

Application

EP 98963336 A

Priority

  • DE 9803287 W
  • DE 19749973 A

Abstract (en)

[origin: DE19749973C1] The present invention relates to lysozym-analogous proteins and peptides having an anti-microbial activity, to the production of the same and the use of said proteins and peptides. These proteins and peptides are recombinantly modified or modified by mutations only as far as their main properties are preserved, especially the anti-microbial properties of the T4 lysozyme and except for the muramidase activity. This invention also relates to recombinant proteins which contain at least the amino acids 126-141 or 143-155 of the T4 lysozyme. This invention further relates to the production of said proteins and peptides from their coding genes, wherein said production comprises carrying out their bio-synthesis in prokaryotic and eukaryotic organisms as well as using chemically-synthesised proteins or peptides. This invention finally relates to the use of these proteins and peptides as medical active agents, as food additives and animal-food additives or as other in vivo and in vitro anti-microbial protection materials or as exogenic proteins in transgenic organisms.

IPC 1-7 (main, further and additional classification)

C12N 15/56; A01N 63/00; A23L 3/3571; A61K 38/47; C12N 9/36; C12N 15/82

IPC 8 full level (invention and additional information)

A23L 3/3571 (2006.01); A01N 63/00 (2006.01); A61K 38/00 (2006.01); A61K 38/46 (2006.01); A61P 31/00 (2006.01); C12N 9/36 (2006.01); C12N 15/09 (2006.01); C12N 15/56 (2006.01); C12N 15/82 (2006.01)

CPC (invention and additional information)

C12N 9/2462 (2013.01); C12N 15/8257 (2013.01); C12N 15/8281 (2013.01); C12N 15/8282 (2013.01); A61K 38/00 (2013.01)

Citation (search report)

See references of WO 9924589A3

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU NL PT SE

EPO simple patent family

DE 19749973 C1 19981022; AU 1867999 A 19990531; AU 751422 B2 20020815; CA 2308618 A1 19990520; EP 1029061 A2 20000823; IL 135987 D0 20010520; JP 2002503443 A 20020205; NZ 504368 A 20021126; US 6515106 B1 20030204; WO 9924589 A2 19990520; WO 9924589 A3 19991104; WO 9924589 B1 20000203

INPADOC legal status

2003-11-05 [18D] DEEMED TO BE WITHDRAWN

- Ref Legal Event Code: 18D

- Effective date: 20030503

2000-08-23 [17P] REQUEST FOR EXAMINATION FILED

- Ref Legal Event Code: 17P

- Effective date: 20000526

2000-08-23 [AK] DESIGNATED CONTRACTING STATES:

- Ref Legal Event Code: AK

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU NL PT SE