EP 1029062 A1 20000823 - INHIBITION OF HUMAN IMMUNODEFICIENCY VIRUS (HIV-1) REPLICATION
Title (en)
INHIBITION OF HUMAN IMMUNODEFICIENCY VIRUS (HIV-1) REPLICATION
Title (de)
INHIBIERUNG DER REPLIKATION DES MENSCHLICHEN IMMUNSCHWÄCHEVIRUS (HIV-1)
Title (fr)
INHIBITION DE LA REPLICATION DU VIRUS DE L'IMMUNODEFICIENCE HUMAINE (VIH-1)
Publication
Application
Priority
- US 9821880 W 19981015
- US 6198497 P 19971016
Abstract (en)
[origin: WO9919496A1] The present invention is directed to an HIV-1-regulated antiviral system. The invention provides constructs and methods for transferring an antiviral enzyme into target cells, wherein the enzyme is under HIV-1 regulation. HIV-1 infection of the targeted cells causes the activation of the antiviral enzyme, and results in the inhibition of viral replication. The HIV-1 controlled antiviral approach can be combined with traditional chemotherapeutic approaches, permitting a significant reduction in antiviral drugs, with decreased side effects, and the maintenance of HIV-1 in a true latent state.
IPC 1-7
IPC 8 full level
A61K 31/513 (2006.01); A61K 35/76 (2006.01); A61K 45/00 (2006.01); A61K 45/06 (2006.01); A61K 48/00 (2006.01); A61P 31/18 (2006.01); A61P 37/04 (2006.01); C12N 1/15 (2006.01); C12N 1/19 (2006.01); C12N 1/21 (2006.01); C12N 5/10 (2006.01); C12N 9/00 (2006.01); C12N 9/12 (2006.01); C12N 15/09 (2006.01); C12N 15/86 (2006.01); A61K 38/00 (2006.01)
CPC (source: EP)
A61P 31/18 (2017.12); A61P 37/04 (2017.12); C12N 9/1205 (2013.01); C12N 9/93 (2013.01); C12N 15/86 (2013.01); A61K 38/00 (2013.01); A61K 48/00 (2013.01); C12N 2740/13043 (2013.01); C12N 2740/13045 (2013.01); C12N 2810/855 (2013.01)
Citation (search report)
See references of WO 9919496A1
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9919496 A1 19990422; AU 1189899 A 19990503; CA 2306444 A1 19990422; EP 1029062 A1 20000823; JP 2001520017 A 20011030
DOCDB simple family (application)
US 9821880 W 19981015; AU 1189899 A 19981015; CA 2306444 A 19981015; EP 98954989 A 19981015; JP 2000516047 A 19981015