Global Patent Index - EP 1029082 A2

EP 1029082 A2 2000-08-23 - DETECTION AND TYPING OF THE $i(iceA) GENE OF $i(HELICOBACTER PYLORI)

Title (en)

DETECTION AND TYPING OF THE $i(iceA) GENE OF $i(HELICOBACTER PYLORI)

Title (de)

NACHWEIS UND TYPISIERUNG DES ICEA GENS VON HELICOBACTER PYLORI

Title (fr)

DETECTION ET TYPAGE D'UN GENE $i(iceA) D'$i(HELICOBACTER PYLORY)

Publication

EP 1029082 A2 (EN)

Application

EP 98961149 A

Priority

  • EP 98961149 A
  • EP 9807106 W
  • EP 97870180 A

Abstract (en)

[origin: WO9924607A2] The present invention relates to a method for detection and/or typing of alleles of the iceA gene of H. pylori present in a biological sample, with said method comprising: i) amplifying polynucleic acids of the iceA gene by use of primers that permit specific amplification either of a fragment of iceA1 variants or of a fragment of iceA2 variants, and/or ii) hybridizing polynucleic acids of the iceA gene, possibly after amplification as in step i), with at least one probe that specifically hybridizes to either iceA1 variants or to iceA2 variants. In order to enable this method, the present invention discloses nucleic acid sequences of iceA1 and iceA2 variants. Primers and probes that can be used to carry out said method are also disclosed. The present invention further relates to diagnostic kits that allow to perform said method. IceA1 and IceA2 protein sequences are also disclosed, as well as antibodies directed against these sequences.

IPC 1-7 (main, further and additional classification)

C12Q 1/68; C07K 14/205; C07K 16/12

IPC 8 full level (invention and additional information)

G01N 33/569 (2006.01); C07K 14/205 (2006.01); C07K 16/12 (2006.01); C12N 15/09 (2006.01); C12Q 1/68 (2006.01)

CPC (invention and additional information)

C12Q 1/689 (2013.01); C07K 14/205 (2013.01)

Citation (search report)

See references of WO 9924607A3

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

EPO simple patent family

WO 9924607 A2 19990520; WO 9924607 A3 19991021; WO 9924607 A9 19990812; AU 1667299 A 19990531; CA 2306254 A1 19990520; EP 1029082 A2 20000823; JP 2001521766 A 20011113

INPADOC legal status


2006-11-22 [18D] DEEMED TO BE WITHDRAWN

- Effective date: 20060601

2000-08-23 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 20000504

2000-08-23 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A2

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

2000-08-23 [AX] REQUEST FOR EXTENSION OF THE EUROPEAN PATENT TO

- Free text: AL PAYMENT 20000504;LT PAYMENT 20000504;LV PAYMENT 20000504;MK PAYMENT 20000504;RO PAYMENT 20000504;SI PAYMENT 20000504