EP 1029082 A2 20000823 - DETECTION AND TYPING OF THE $i(iceA) GENE OF $i(HELICOBACTER PYLORI)
Title (en)
DETECTION AND TYPING OF THE $i(iceA) GENE OF $i(HELICOBACTER PYLORI)
Title (de)
NACHWEIS UND TYPISIERUNG DES ICEA GENS VON HELICOBACTER PYLORI
Title (fr)
DETECTION ET TYPAGE D'UN GENE $i(iceA) D'$i(HELICOBACTER PYLORY)
Publication
Application
Priority
- EP 98961149 A 19981106
- EP 9807106 W 19981106
- EP 97870180 A 19971106
Abstract (en)
[origin: WO9924607A2] The present invention relates to a method for detection and/or typing of alleles of the iceA gene of H. pylori present in a biological sample, with said method comprising: i) amplifying polynucleic acids of the iceA gene by use of primers that permit specific amplification either of a fragment of iceA1 variants or of a fragment of iceA2 variants, and/or ii) hybridizing polynucleic acids of the iceA gene, possibly after amplification as in step i), with at least one probe that specifically hybridizes to either iceA1 variants or to iceA2 variants. In order to enable this method, the present invention discloses nucleic acid sequences of iceA1 and iceA2 variants. Primers and probes that can be used to carry out said method are also disclosed. The present invention further relates to diagnostic kits that allow to perform said method. IceA1 and IceA2 protein sequences are also disclosed, as well as antibodies directed against these sequences.
IPC 1-7
IPC 8 full level
C07K 14/205 (2006.01); C07K 16/12 (2006.01); C12N 15/09 (2006.01); C12Q 1/68 (2006.01); C12Q 1/689 (2018.01); G01N 33/569 (2006.01)
CPC (source: EP)
C07K 14/205 (2013.01); C12Q 1/689 (2013.01)
Citation (search report)
See references of WO 9924607A2
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9924607 A2 19990520; WO 9924607 A3 19991021; WO 9924607 A9 19990812; AU 1667299 A 19990531; CA 2306254 A1 19990520; EP 1029082 A2 20000823; JP 2001521766 A 20011113
DOCDB simple family (application)
EP 9807106 W 19981106; AU 1667299 A 19981106; CA 2306254 A 19981106; EP 98961149 A 19981106; JP 2000519600 A 19981106