Global Patent Index - EP 1030557 A1

EP 1030557 A1 2000-08-30 - PROTEIN DELIVERY BY SECRETORY GLAND EXPRESSION

Title (en)

PROTEIN DELIVERY BY SECRETORY GLAND EXPRESSION

Title (de)

PROTEINPRODUKTION DURCH EXPRESSION IN SEKRETORISCHE DRÜSEN

Title (fr)

ADMINISTRATION DE PROTEINES PAR L'EXPRESSION DES GLANDES SECRETOIRES

Publication

EP 1030557 A1 (EN)

Application

EP 98950707 A

Priority

  • US 9820199 W
  • US 94293997 A

Abstract (en)

[origin: WO9917610A1] Secretory gland cells, particularly pancreatic, hepatic, and salivary gland cells, are genetically altered to operatively incorporate a gene which expresses a protein which has a desired therapeutic effect on a mammalian subject. The expressed protein is secreted directly into the bloodstream to obtain therapeutic levels of the protein thereby treating the patient in need of the protein. The transformed secretory gland cells provide long term or short term therapies for diseases associated with a deficiency in a particular protein or which are amenable to treatment by overexpression of a protein.

IPC 1-7 (main, further and additional classification)

A01N 43/04; A01N 63/00; C12N 13/00

IPC 8 full level (invention and additional information)

C12N 15/09 (2006.01); A61K 38/00 (2006.01); A61K 38/16 (2006.01); A61K 38/17 (2006.01); A61K 38/21 (2006.01); A61K 38/22 (2006.01); A61K 38/27 (2006.01); A61K 38/28 (2006.01); A61K 38/36 (2006.01); A61K 38/43 (2006.01); A61K 39/395 (2006.01); A61K 48/00 (2006.01); A61P 3/10 (2006.01)

CPC (invention and additional information)

A61K 38/27 (2013.01); A61K 38/28 (2013.01); A61K 48/00 (2013.01)

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

EPO simple patent family

WO 9917610 A1 19990415; AU 744279 B2 20020221; AU 9668998 A 19990427; CA 2304803 A1 19990415; EP 1030557 A1 20000830; EP 1030557 A4 20020731; JP 2001518316 A 20011016

INPADOC legal status


2003-05-07 [18D] DEEMED TO BE WITHDRAWN

- Effective date: 20020830

2002-07-31 [A4] SUPPLEMENTARY SEARCH REPORT

- Effective date: 20020614

2002-07-31 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A4

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

2002-06-19 [RIC1] CLASSIFICATION (CORRECTION)

- Free text: 7A 01N 43/04 A, 7A 01N 63/00 B, 7C 12N 13/00 B, 7A 61K 48/00 B

2000-08-30 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 20000425

2000-08-30 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A1

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE