EP 1030557 A1 20000830 - PROTEIN DELIVERY BY SECRETORY GLAND EXPRESSION
Title (en)
PROTEIN DELIVERY BY SECRETORY GLAND EXPRESSION
Title (de)
PROTEINPRODUKTION DURCH EXPRESSION IN SEKRETORISCHE DRÜSEN
Title (fr)
ADMINISTRATION DE PROTEINES PAR L'EXPRESSION DES GLANDES SECRETOIRES
Publication
Application
Priority
- US 9820199 W 19980924
- US 94293997 A 19971002
Abstract (en)
[origin: WO9917610A1] Secretory gland cells, particularly pancreatic, hepatic, and salivary gland cells, are genetically altered to operatively incorporate a gene which expresses a protein which has a desired therapeutic effect on a mammalian subject. The expressed protein is secreted directly into the bloodstream to obtain therapeutic levels of the protein thereby treating the patient in need of the protein. The transformed secretory gland cells provide long term or short term therapies for diseases associated with a deficiency in a particular protein or which are amenable to treatment by overexpression of a protein.
IPC 1-7
IPC 8 full level
A61K 38/00 (2006.01); A61K 38/16 (2006.01); A61K 38/17 (2006.01); A61K 38/21 (2006.01); A61K 38/22 (2006.01); A61K 38/27 (2006.01); A61K 38/28 (2006.01); A61K 38/36 (2006.01); A61K 38/43 (2006.01); A61K 39/395 (2006.01); A61K 48/00 (2006.01); A61P 3/10 (2006.01); C12N 15/09 (2006.01)
CPC (source: EP)
A61K 38/27 (2013.01); A61K 38/28 (2013.01); A61P 3/10 (2017.12); A61K 48/00 (2013.01)
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9917610 A1 19990415; AU 744279 B2 20020221; AU 9668998 A 19990427; CA 2304803 A1 19990415; EP 1030557 A1 20000830; EP 1030557 A4 20020731; JP 2001518316 A 20011016
DOCDB simple family (application)
US 9820199 W 19980924; AU 9668998 A 19980924; CA 2304803 A 19980924; EP 98950707 A 19980924; JP 2000514522 A 19980924