EP 1032383 A1 20000906 - ANTIBACTERIAL CARBAPENEMS, COMPOSITIONS AND METHODS OF TREATMEMT
Title (en)
ANTIBACTERIAL CARBAPENEMS, COMPOSITIONS AND METHODS OF TREATMEMT
Title (de)
ANTIBAKTERIELLE CARBAPENEME, ZUSAMMENSETZUNGEN UND VERFAHREN ZUR BEHANDLUNG
Title (fr)
CARBAPENEMES ANTIBACTERIENS, COMPOSITIONS ET METHODES DE TRAITEMENT
Publication
Application
Priority
- GB 9810174 A 19980513
- US 9822009 W 19981019
- US 6324297 P 19971023
Abstract (en)
[origin: WO9920269A1] Carbapenems substituted with a naphthosultam at position 2 and linked through a CH2 group are disclosed. Pharmaceutical compositions and methods of treatment are also included. The naphtosultam is substituted with at least one cationic group -A-Q-L-B : (I). A-Q-L-B represents a side chain wherein in part: Q is formula (II) and (B) represents formulae (III) or (IV). The carbapenenems of the present invention are useful against gram positive microorganisms, especially methicillin resistant Staphylococci.
IPC 1-7
IPC 8 full level
A61K 31/4995 (2006.01); A61K 31/506 (2006.01); A61P 31/04 (2006.01); C07D 477/14 (2006.01); C07D 519/00 (2006.01); C07D 521/00 (2006.01)
CPC (source: EP)
A61P 31/04 (2017.12); C07D 231/12 (2013.01); C07D 233/56 (2013.01); C07D 249/08 (2013.01); C07D 477/14 (2013.01)
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU NL PT SE
DOCDB simple family (publication)
WO 9920269 A1 19990429; AU 1100399 A 19990510; AU 735599 B2 20010712; CA 2306965 A1 19990429; EP 1032383 A1 20000906; EP 1032383 A4 20011121; JP 2001520191 A 20011030
DOCDB simple family (application)
US 9822009 W 19981019; AU 1100399 A 19981019; CA 2306965 A 19981019; EP 98953687 A 19981019; JP 2000516666 A 19981019