Global Patent Index - EP 1032383 A1

EP 1032383 A1 2000-09-06 - ANTIBACTERIAL CARBAPENEMS, COMPOSITIONS AND METHODS OF TREATMEMT

Title (en)

ANTIBACTERIAL CARBAPENEMS, COMPOSITIONS AND METHODS OF TREATMEMT

Title (de)

ANTIBAKTERIELLE CARBAPENEME, ZUSAMMENSETZUNGEN UND VERFAHREN ZUR BEHANDLUNG

Title (fr)

CARBAPENEMES ANTIBACTERIENS, COMPOSITIONS ET METHODES DE TRAITEMENT

Publication

EP 1032383 A1 (EN)

Application

EP 98953687 A

Priority

  • GB 9810174 A
  • US 9822009 W
  • US 6324297 P

Abstract (en)

[origin: WO9920269A1] Carbapenems substituted with a naphthosultam at position 2 and linked through a CH2 group are disclosed. Pharmaceutical compositions and methods of treatment are also included. The naphtosultam is substituted with at least one cationic group -A-Q-L-B : (I). A-Q-L-B represents a side chain wherein in part: Q is formula (II) and (B) represents formulae (III) or (IV). The carbapenenems of the present invention are useful against gram positive microorganisms, especially methicillin resistant Staphylococci.

IPC 1-7 (main, further and additional classification)

A61K 31/40; C07D 477/14

IPC 8 full level (invention and additional information)

C07D 519/00 (2006.01); A61K 31/4995 (2006.01); A61K 31/506 (2006.01); A61P 31/04 (2006.01); C07D 477/14 (2006.01); C07D 521/00 (2006.01)

CPC (invention and additional information)

C07D 231/12 (2013.01); C07D 233/56 (2013.01); C07D 249/08 (2013.01); C07D 477/14 (2013.01)

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU NL PT SE

EPO simple patent family

WO 9920269 A1 19990429; AU 1100399 A 19990510; AU 735599 B2 20010712; CA 2306965 A1 19990429; EP 1032383 A1 20000906; EP 1032383 A4 20011121; JP 2001520191 A 20011030

INPADOC legal status


2003-01-29 [18R] REFUSED

- Effective date: 20020907

2002-05-02 [17Q] FIRST EXAMINATION REPORT

- Effective date: 20020314

2001-11-21 [A4] SUPPLEMENTARY SEARCH REPORT

- Effective date: 20011009

2001-11-21 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A4

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU NL PT SE

2000-09-06 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 20000523

2000-09-06 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A1

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU NL PT SE

2000-09-06 [AX] REQUEST FOR EXTENSION OF THE EUROPEAN PATENT TO

- Free text: AL PAYMENT 20000523;LT PAYMENT 20000523;LV PAYMENT 20000523;MK PAYMENT 20000523;RO PAYMENT 20000523;SI PAYMENT 20000523