EP 1032427 A2 20000906 - CONJUGATES OF CYTOKINES AND DRUGS OR GENES FOR TREATING PROLIFERATING CELLS
Title (en)
CONJUGATES OF CYTOKINES AND DRUGS OR GENES FOR TREATING PROLIFERATING CELLS
Title (de)
CYTOKINKONJUGATE MIT PHARMAZEUTISCHE WIRKSTOFFE ODER GENEN FÜR THERAPIE DER ZELLPROLIFERATION
Title (fr)
PRODUIT A ACTIVITE PROLIFERATIVE UTILE POUR TRAITER DES CELLULES PROLIFERATIVES
Publication
Application
Priority
- GB 9803509 W 19981125
- GB 9724838 A 19971126
Abstract (en)
[origin: WO9926660A2] A product comprising a proliferatively active moiety, typically a cytokine or growth factor which has a high affinity receptor, linked to a biologically active agent which agent preferentially or selectively affects proliferating cells. An active promoter of proliferation, for example an active IL-2, is beneficially used to deliver pharmacologically desirable species to cells whose proliferation is not desired. For example some medicaments of the invention control or inhibit proliferation using a molecule which contains an active promoter of proliferation. The biologically active agent is usually selected from the group consisting of antiproliferative drugs, compounds which interfere with nucleotide synthesis, radioisotopes, gene sequences and antisense nucleotide sequences.
IPC 1-7
IPC 8 full level
A61K 38/00 (2006.01); A61K 38/22 (2006.01); A61K 45/00 (2006.01); A61K 47/48 (2006.01); A61P 43/00 (2006.01)
CPC (source: EP)
A61K 47/642 (2017.07); A61P 43/00 (2017.12)
Citation (search report)
See references of WO 9926660A2
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9926660 A2 19990603; WO 9926660 A3 19991014; AU 1249999 A 19990615; CA 2311733 A1 19990603; EP 1032427 A2 20000906; GB 9724838 D0 19980121; JP 2001523731 A 20011127; NZ 504625 A 20021220; ZA 9810759 B 20000525
DOCDB simple family (application)
GB 9803509 W 19981125; AU 1249999 A 19981125; CA 2311733 A 19981125; EP 98955771 A 19981125; GB 9724838 A 19971126; JP 2000521861 A 19981125; NZ 50462598 A 19981125; ZA 9810759 A 19981125