Global Patent Index - EP 1032427 A2

EP 1032427 A2 2000-09-06 - CONJUGATES OF CYTOKINES AND DRUGS OR GENES FOR TREATING PROLIFERATING CELLS

Title (en)

CONJUGATES OF CYTOKINES AND DRUGS OR GENES FOR TREATING PROLIFERATING CELLS

Title (de)

CYTOKINKONJUGATE MIT PHARMAZEUTISCHE WIRKSTOFFE ODER GENEN FÜR THERAPIE DER ZELLPROLIFERATION

Title (fr)

PRODUIT A ACTIVITE PROLIFERATIVE UTILE POUR TRAITER DES CELLULES PROLIFERATIVES

Publication

EP 1032427 A2 (EN)

Application

EP 98955771 A

Priority

  • GB 9803509 W
  • GB 9724838 A

Abstract (en)

[origin: WO9926660A2] A product comprising a proliferatively active moiety, typically a cytokine or growth factor which has a high affinity receptor, linked to a biologically active agent which agent preferentially or selectively affects proliferating cells. An active promoter of proliferation, for example an active IL-2, is beneficially used to deliver pharmacologically desirable species to cells whose proliferation is not desired. For example some medicaments of the invention control or inhibit proliferation using a molecule which contains an active promoter of proliferation. The biologically active agent is usually selected from the group consisting of antiproliferative drugs, compounds which interfere with nucleotide synthesis, radioisotopes, gene sequences and antisense nucleotide sequences.

IPC 1-7 (main, further and additional classification)

A61K 47/48

IPC 8 full level (invention and additional information)

A61K 38/00 (2006.01); A61K 38/22 (2006.01); A61K 45/00 (2006.01); A61K 47/48 (2006.01); A61P 43/00 (2006.01)

CPC (invention and additional information)

A61K 47/48269 (2013.01)

Citation (search report)

See references of WO 9926660A3

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

EPO simple patent family

WO 9926660 A2 19990603; WO 9926660 A3 19991014; AU 1249999 A 19990615; CA 2311733 A1 19990603; EP 1032427 A2 20000906; GB 9724838 D0 19980121; JP 2001523731 A 20011127; NZ 504625 A 20021220; ZA 9810759 B 20000525

INPADOC legal status


2005-12-07 [18D] DEEMED TO BE WITHDRAWN

- Effective date: 20050601

2003-02-26 [17Q] FIRST EXAMINATION REPORT

- Effective date: 20030110

2000-09-06 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 20000624

2000-09-06 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A2

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE