EP 1033910 A1 20000913 - DIPEPTIDE APOPTOSIS INHIBITORS AND THE USE THEREOF
Title (en)
DIPEPTIDE APOPTOSIS INHIBITORS AND THE USE THEREOF
Title (de)
DIPEPTID-APOPTOSE-INHIBITOREN UND DEREN VERWENDUNG
Title (fr)
DIPEPTIDES INHIBITEURS DE L'APOPTOSE ET UTILISATION DE CES DERNIERS
Publication
Application
Priority
- US 9821232 W 19981009
- US 6167697 P 19971010
Abstract (en)
[origin: WO9918781A1] The present invention is directed to novel dipeptides thereof, represented by general Formula (I) where R1-R3 and AA are defined herein. The present invention relates to the discovery that compounds having Formula (I) are potent inhibitors of apoptotic cell death. Therefore, the inhibitors of this invention can retard or block cell death in a variety of clinical conditions in which the loss of cells, tissues or entire organs occurs.
IPC 1-7
IPC 8 full level
A61K 38/00 (2006.01); A61P 3/10 (2006.01); A61P 7/06 (2006.01); A61P 9/04 (2006.01); A61P 9/10 (2006.01); A61P 13/12 (2006.01); A61P 19/02 (2006.01); A61P 25/14 (2006.01); A61P 25/16 (2006.01); A61P 25/28 (2006.01); A61P 29/00 (2006.01); A61P 37/04 (2006.01); A61P 37/06 (2006.01); C07C 237/12 (2006.01); C07C 237/22 (2006.01); C07C 271/22 (2006.01); C07C 323/59 (2006.01); C07C 323/60 (2006.01); C07D 233/54 (2006.01); C07D 277/16 (2006.01); C07K 5/06 (2006.01); C12N 1/04 (2006.01); C12N 5/00 (2006.01)
CPC (source: EP KR)
A61P 3/10 (2017.12 - EP); A61P 7/06 (2017.12 - EP); A61P 9/04 (2017.12 - EP); A61P 9/10 (2017.12 - EP); A61P 13/12 (2017.12 - EP); A61P 19/02 (2017.12 - EP); A61P 25/14 (2017.12 - EP); A61P 25/16 (2017.12 - EP); A61P 25/28 (2017.12 - EP); A61P 29/00 (2017.12 - EP); A61P 37/04 (2017.12 - EP); A61P 37/06 (2017.12 - EP); C07C 233/64 (2013.01 - KR); C07C 237/22 (2013.01 - EP KR); C07C 271/22 (2013.01 - EP KR); C07C 323/60 (2013.01 - EP KR); C07D 233/64 (2013.01 - EP); C07D 277/16 (2013.01 - EP KR); C07K 5/06191 (2013.01 - EP); A61K 38/00 (2013.01 - EP); C12N 2810/40 (2013.01 - EP)
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9918781 A1 19990422; AU 741203 B2 20011122; AU 9793098 A 19990503; BR 9814817 A 20020108; CA 2306692 A1 19990422; CA 2306692 C 20100921; CN 1138472 C 20040218; CN 1301131 A 20010627; EA 200000409 A1 20001030; EP 1033910 A1 20000913; EP 1033910 A4 20041124; JP 2001519358 A 20011023; JP 4439111 B2 20100324; KR 100580333 B1 20060516; KR 20010031053 A 20010416; NO 20001323 D0 20000314; NO 20001323 L 20000613
DOCDB simple family (application)
US 9821232 W 19981009; AU 9793098 A 19981009; BR 9814817 A 19981009; CA 2306692 A 19981009; CN 98810022 A 19981009; EA 200000409 A 19981009; EP 98952166 A 19981009; JP 2000515426 A 19981009; KR 20007003882 A 20000410; NO 20001323 A 20000314