Global Patent Index - EP 1034186 A2

EP 1034186 A2 2000-09-13 - SYNTHETIC PEPTIDES CONTAINING CITRULLINE RECOGNIZED BY RHEUMATOID ARTHRITIS SERA AS TOOLS FOR DIAGNOSIS AND TREATMENT

Title (en)

SYNTHETIC PEPTIDES CONTAINING CITRULLINE RECOGNIZED BY RHEUMATOID ARTHRITIS SERA AS TOOLS FOR DIAGNOSIS AND TREATMENT

Title (de)

CITRULLIN-ENTHALTENDE SYNTHETISCHE PEPTIDE, REAKTIV MIT SEREN VON PATIENTEN MIT RHEUMATISCHE ARTHRITIS, ZUR DIAGNOSE UND BEHANDLUNG

Title (fr)

PEPTIDES SYNTHETIQUES CONTENANT UNE CITRULLINE RECONNUE PAR LES SERUMS DE MALADES ATTEINTS DE POLYARTHRITE RHUMATOIDE COMME DES OUTILS DE DIAGNOSTIC ET DE TRAITEMENT

Publication

EP 1034186 A2 (EN)

Application

EP 98965715 A

Priority

  • EP 98965715 A
  • EP 9807714 W
  • EP 97870195 A
  • EP 98870078 A

Abstract (en)

[origin: WO9928344A2] The present invention relates to a method of producing certain peptides containing citrulline residues that constitute immunogenic determinants of antibodies present in sera from patients with rheumatoid arthritis and wherein the presence of at least one citrulline is a prerequisite for reacting with said antibodies. The invention also relates to a method of producing said antibodies and the use of said peptides for diagnosis and treatment of rheumatoid arthritis.

IPC 1-7 (main, further and additional classification)

C07K 14/47; A61K 38/17; C07K 1/107; C07K 16/18; G01N 33/564

IPC 8 full level (invention and additional information)

G01N 33/564 (2006.01); A61K 38/17 (2006.01); A61K 39/395 (2006.01); A61P 19/02 (2006.01); A61P 29/00 (2006.01); C07K 1/107 (2006.01); C07K 14/47 (2006.01); C07K 16/18 (2006.01); C07K 16/42 (2006.01); C12N 15/09 (2006.01); C12P 21/02 (2006.01); A61K 38/00 (2006.01)

CPC (invention and additional information)

C07K 1/107 (2013.01); C07K 14/4713 (2013.01); A61K 38/00 (2013.01); C07K 2319/00 (2013.01)

Citation (search report)

See references of WO 9928344A3

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

EPO simple patent family

WO 9928344 A2 19990610; WO 9928344 A3 19990812; AU 2155899 A 19990616; CA 2309534 A1 19990610; CZ 20001963 A3 20020417; EP 1034186 A2 20000913; HU 0004338 A2 20010228; JP 2002512939 A 20020508; PL 344534 A1 20011105

INPADOC legal status


2003-12-03 [18D] DEEMED TO BE WITHDRAWN

- Ref Legal Event Code: 18D

- Effective date: 20030601

2000-09-13 [17P] REQUEST FOR EXAMINATION FILED

- Ref Legal Event Code: 17P

- Effective date: 20000613

2000-09-13 [AK] DESIGNATED CONTRACTING STATES:

- Ref Legal Event Code: AK

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

2000-09-13 [AX] REQUEST FOR EXTENSION OF THE EUROPEAN PATENT TO

- Ref Legal Event Code: AX

- Free Format Text: AL PAYMENT 20000613;LT PAYMENT 20000613;LV PAYMENT 20000613;MK PAYMENT 20000613;RO PAYMENT 20000613;SI PAYMENT 20000613