Global Patent Index - EP 1034263 A1

EP 1034263 A1 2000-09-13 - THE NIP3 FAMILY OF PROTEINS

Title (en)

THE NIP3 FAMILY OF PROTEINS

Title (de)

DIE NIP3 PROTEINFAMILIE

Title (fr)

FAMILLE NIP3 DE PROTEINES

Publication

EP 1034263 A1 (EN)

Application

EP 98955851 A

Priority

  • IB 9801959 W
  • US 6664997 P
  • US 9815998 P

Abstract (en)

[origin: WO9927093A2] The present invention provides an isolated and purified Nip, Nix and Nox proteins. There is also provided a method for inducing apoptosis in cells by transfecting a cell with a Nip, Nix and Nox proteins. Additionally, there is provided a method for inducing apoptosis in cells by creating antibodies which recognize a specific Nip, Nix and Nox proteins in a muscle or skin of a patient. A method for inducing apoptosis in cells by creating a transgene overexpressing the gene for the Nip, Nix and Nox proteins is also provided. A transgenic animal and progeny thereof is provided having an expression factor consisting essentially of a Nip, Nix and Nox proteins selected from the group consisting essentially of Seq. ID No:1 through 6.

IPC 1-7 (main, further and additional classification)

C12N 15/12; A01K 67/027; C07K 14/47; C07K 16/18; C12N 5/10

IPC 8 full level (invention and additional information)

C07K 14/47 (2006.01); C12N 15/12 (2006.01); A61K 48/00 (2006.01)

CPC (invention and additional information)

C07K 14/4747 (2013.01); A01K 2217/05 (2013.01); A61K 48/00 (2013.01)

Citation (search report)

See references of WO 9927093A3

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

EPO simple patent family

WO 9927093 A2 19990603; WO 9927093 A3 19990812; AU 1255999 A 19990615; CA 2311170 A1 19990603; EP 1034263 A1 20000913

INPADOC legal status


2003-04-16 [18D] DEEMED TO BE WITHDRAWN

- Effective date: 20021001

2002-05-02 [17Q] FIRST EXAMINATION REPORT

- Effective date: 20020318

2000-09-13 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 20000605

2000-09-13 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A1

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE