Global Patent Index - EP 1034264 A1

EP 1034264 A1 2000-09-13 - SPLICE VARIANTS FOR HUMAN 5-HT4 SEROTONIN RECEPTOR AND THEIR APPLICATIONS, IN PARTICULAR FOR SCREENING

Title (en)

SPLICE VARIANTS FOR HUMAN 5-HT4 SEROTONIN RECEPTOR AND THEIR APPLICATIONS, IN PARTICULAR FOR SCREENING

Title (de)

SPLEISSVARIANTEN VOM MENSCHLICHEN 5-HT4 SEROTONINREZEPTOR UND DEREN ANWENDUNGEN, INSBESONDERE FÜR SCREENING-VERFAHREN

Title (fr)

VARIANTS D'EPISSAGE DU RECEPTEUR SEROTONINERGIQUE 5-HT4 HUMAIN ET LEURS APPLICATIONS, NOTAMMENT POUR LE CRIBLAGE

Publication

EP 1034264 A1 (FR)

Application

EP 98958279 A

Priority

  • FR 9802560 W
  • FR 9715037 A

Abstract (en)

[origin: FR2771741A1] The invention concerns an isolated polypeptide constitutive of splice variants for human serotonin receptor whereof the amino acid sequence is selected among the sequence SEQ ID N DEG 2 of the 5-HT4(c) polypeptide variant or the sequence SEQ ID N DEG 4 of the 5-HT4(d) polypeptide variant, or any polypeptide fragment or biologically active derivative thereof. The invention also concerns the inverse agonist effect of ML 10375 on 5-HT4(c) and 5-HT4(d) receptors.

IPC 1-7 (main, further and additional classification)

C12N 15/12; C12N 5/10; C12Q 1/68; C07K 14/705; C07K 16/28; A61K 31/445; A61K 31/70; A61K 38/17; A61K 39/395; G01N 33/50; G01N 33/53; G01N 33/68

IPC 8 full level (invention and additional information)

G01N 33/50 (2006.01); A61K 31/445 (2006.01); A61K 31/711 (2006.01); A61K 38/00 (2006.01); A61K 39/395 (2006.01); A61K 48/00 (2006.01); A61P 1/00 (2006.01); A61P 25/00 (2006.01); C07D 211/14 (2006.01); C07K 14/705 (2006.01); C07K 16/28 (2006.01); C12N 5/10 (2006.01); C12N 15/09 (2006.01); C12N 15/12 (2006.01); C12Q 1/68 (2006.01); G01N 33/15 (2006.01); G01N 33/53 (2006.01); G01N 33/68 (2006.01)

CPC (invention and additional information)

C07K 14/70571 (2013.01); A61K 31/445 (2013.01); A61K 38/00 (2013.01)

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

EPO simple patent family

FR 2771741 A1 19990604; FR 2771741 B1 20010713; CA 2310541 A1 19990610; EP 1034264 A1 20000913; JP 2002507385 A 20020312; US 6506580 B1 20030114; WO 9928456 A1 19990610

INPADOC legal status


2005-12-14 [18W] WITHDRAWN

- Effective date: 20051022

2005-07-20 [RTI1] TITLE (CORRECTION)

- Free text: SPLICE VARIANTS FOR HUMAN 5-HT4 SEROTONIN RECEPTOR AND THEIR APPLICATIONS, IN PARTICULAR FOR SCREENING

2004-06-16 [17Q] FIRST EXAMINATION REPORT

- Effective date: 20040503

2000-09-13 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 20000529

2000-09-13 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A1

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE