EP 1034264 A1 20000913 - SPLICE VARIANTS FOR HUMAN 5-HT4 SEROTONIN RECEPTOR AND THEIR APPLICATIONS, IN PARTICULAR FOR SCREENING
Title (en)
SPLICE VARIANTS FOR HUMAN 5-HT4 SEROTONIN RECEPTOR AND THEIR APPLICATIONS, IN PARTICULAR FOR SCREENING
Title (de)
SPLEISSVARIANTEN VOM MENSCHLICHEN 5-HT4 SEROTONINREZEPTOR UND DEREN ANWENDUNGEN, INSBESONDERE FÜR SCREENING-VERFAHREN
Title (fr)
VARIANTS D'EPISSAGE DU RECEPTEUR SEROTONINERGIQUE 5-HT4 HUMAIN ET LEURS APPLICATIONS, NOTAMMENT POUR LE CRIBLAGE
Publication
Application
Priority
- FR 9802560 W 19981127
- FR 9715037 A 19971128
Abstract (en)
[origin: FR2771741A1] The invention concerns an isolated polypeptide constitutive of splice variants for human serotonin receptor whereof the amino acid sequence is selected among the sequence SEQ ID N DEG 2 of the 5-HT4(c) polypeptide variant or the sequence SEQ ID N DEG 4 of the 5-HT4(d) polypeptide variant, or any polypeptide fragment or biologically active derivative thereof. The invention also concerns the inverse agonist effect of ML 10375 on 5-HT4(c) and 5-HT4(d) receptors.
IPC 1-7
C12N 15/12; C12N 5/10; C12Q 1/68; C07K 14/705; C07K 16/28; A61K 31/445; A61K 31/70; A61K 38/17; A61K 39/395; G01N 33/50; G01N 33/53; G01N 33/68
IPC 8 full level
A61K 31/445 (2006.01); A61K 31/711 (2006.01); A61K 38/00 (2006.01); A61K 39/395 (2006.01); A61K 48/00 (2006.01); A61P 1/00 (2006.01); A61P 25/00 (2006.01); C07D 211/14 (2006.01); C07K 14/705 (2006.01); C07K 16/28 (2006.01); C12N 5/10 (2006.01); C12N 15/09 (2006.01); C12N 15/12 (2006.01); C12Q 1/68 (2006.01); G01N 33/15 (2006.01); G01N 33/50 (2006.01); G01N 33/53 (2006.01); G01N 33/68 (2006.01)
CPC (source: EP US)
A61K 31/445 (2013.01 - EP US); A61P 1/00 (2017.12 - EP); A61P 25/00 (2017.12 - EP); C07K 14/70571 (2013.01 - EP US); A61K 38/00 (2013.01 - EP US)
Citation (search report)
See references of WO 9928456A1
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
FR 2771741 A1 19990604; FR 2771741 B1 20010713; CA 2310541 A1 19990610; EP 1034264 A1 20000913; JP 2002507385 A 20020312; US 6506580 B1 20030114; WO 9928456 A1 19990610
DOCDB simple family (application)
FR 9715037 A 19971128; CA 2310541 A 19981127; EP 98958279 A 19981127; FR 9802560 W 19981127; JP 2000523333 A 19981127; US 55531300 A 20000919