Global Patent Index - EP 1036086 A1

EP 1036086 A1 2000-09-20 - CASPASE-14 POLYPEPTIDES

Title (en)

CASPASE-14 POLYPEPTIDES

Title (de)

POLYPEPTIDE VON CASPASE-14

Title (fr)

POLYPEPTIDES DE CASPASE-14

Publication

EP 1036086 A1 (EN)

Application

EP 98950774 A

Priority

  • US 9820452 W
  • US 6359297 P
  • US 7605098 P

Abstract (en)

[origin: WO9923106A1] The present invention relates to a novel Caspase-14 protein (also called ERICE) which is a novel effector of apoptosis. In particular, isolated nucleic acid molecules are provided encoding the human Caspase-14 protein. Caspase-14 polypeptides are also provided as are vectors, host cells and recombinant methods for producing the same. The invention further relates to screening methods for identifying agonists and antagonists of Caspase-14 activity. Also provided are therapeutic methods for treating diseases and disorders associated with apoptosis.

IPC 1-7 (main, further and additional classification)

C07H 21/04; C12N 1/14; C12N 1/20; C12N 5/00; C12N 9/48; C12N 15/00; C12Q 1/68

IPC 8 full level (invention and additional information)

C12N 15/09 (2006.01); A61K 38/00 (2006.01); A61K 45/00 (2006.01); A61P 9/00 (2006.01); A61P 35/00 (2006.01); A61P 43/00 (2006.01); C07K 14/47 (2006.01); C12N 1/15 (2006.01); C12N 1/21 (2006.01); C12N 5/10 (2006.01); C12N 9/48 (2006.01); C12N 9/64 (2006.01); C12Q 1/68 (2006.01)

CPC (invention and additional information)

C12N 9/6475 (2013.01); C07K 14/4747 (2013.01)

Citation (search report)

See references of WO 9923106A1

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

EPO simple patent family

WO 9923106 A1 19990514; AU 750170 B2 20020711; AU 9673898 A 19990524; CA 2308112 A1 19990514; EP 1036086 A1 20000920; JP 2001521730 A 20011113

INPADOC legal status


2003-05-28 [18W] WITHDRAWN

- Effective date: 20030402

2000-09-20 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 20000526

2000-09-20 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A1

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE