EP 1037608 A1 20000927 - ACOUSTICALLY ACTIVATED LOCALIZED DRUG DELIVERY
Title (en)
ACOUSTICALLY ACTIVATED LOCALIZED DRUG DELIVERY
Title (de)
AKUSTISCH AKTIVIERBARE LOKALISIERTE WIRKSTOFFZUFUHR
Title (fr)
LIBERATION DE MEDICAMENT LOCALISEE, ACTIVEE PAR VOIE ACOUSTIQUE
Publication
Application
Priority
- US 9820046 W 19980923
- US 5977497 P 19970923
Abstract (en)
[origin: WO9915151A1] A method for administering a drug to a selected site in a patient includes the steps of (a) administering a composition including a micellar drug carrier having a hydrophobic core and an effective amount of the drug disposed in the hydrophobic core; and (b) applying ultrasonic energy to the selected site such that the drug is released from the hydrophobic core to the selected site. Preferably, the drug carrier is a triblock copolymer, such as a poly(ethylene oxide)-poly(propylene oxide)-poly(ethylene oxide) block copolymer having a molecular weight of about 6500. The drug is preferably an antineoplastic agent such as doxorubicin.
IPC 1-7
IPC 8 full level
A61K 9/00 (2006.01); A61K 9/107 (2006.01)
CPC (source: EP)
A61K 9/0009 (2013.01); A61K 9/1075 (2013.01)
Citation (search report)
See references of WO 9915151A1
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9915151 A1 19990401; CA 2304134 A1 19990401; EP 1037608 A1 20000927
DOCDB simple family (application)
US 9820046 W 19980923; CA 2304134 A 19980923; EP 98950671 A 19980923