Global Patent Index - EP 1037608 A1

EP 1037608 A1 2000-09-27 - ACOUSTICALLY ACTIVATED LOCALIZED DRUG DELIVERY

Title (en)

ACOUSTICALLY ACTIVATED LOCALIZED DRUG DELIVERY

Title (de)

AKUSTISCH AKTIVIERBARE LOKALISIERTE WIRKSTOFFZUFUHR

Title (fr)

LIBERATION DE MEDICAMENT LOCALISEE, ACTIVEE PAR VOIE ACOUSTIQUE

Publication

EP 1037608 A1 (EN)

Application

EP 98950671 A

Priority

  • US 9820046 W
  • US 5977497 P

Abstract (en)

[origin: WO9915151A1] A method for administering a drug to a selected site in a patient includes the steps of (a) administering a composition including a micellar drug carrier having a hydrophobic core and an effective amount of the drug disposed in the hydrophobic core; and (b) applying ultrasonic energy to the selected site such that the drug is released from the hydrophobic core to the selected site. Preferably, the drug carrier is a triblock copolymer, such as a poly(ethylene oxide)-poly(propylene oxide)-poly(ethylene oxide) block copolymer having a molecular weight of about 6500. The drug is preferably an antineoplastic agent such as doxorubicin.

IPC 1-7 (main, further and additional classification)

A61K 9/10; A61K 47/32

IPC 8 full level (invention and additional information)

A61K 9/00 (2006.01); A61K 9/107 (2006.01)

CPC (invention and additional information)

A61K 9/1075 (2013.01); A61K 9/0009 (2013.01)

Citation (search report)

See references of WO 9915151A1

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

EPO simple patent family

WO 9915151 A1 19990401; CA 2304134 A1 19990401; EP 1037608 A1 20000927

INPADOC legal status


2004-11-10 [18W] WITHDRAWN

- Effective date: 20040903

2000-09-27 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 20000323

2000-09-27 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A1

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE