Global patent index - EP 1037668 A1

EP 1037668 A1 2000-09-27 - TRANSFECTION PARTICLES

Title (en)

TRANSFECTION PARTICLES

Title (de)

TRANSFEKTION PARTIKELN

Title (fr)

PARTICULES DE TRANSFECTION

Publication

EP 1037668 A1 (EN)

Application

EP 98962400 A

Priority

  • EP 98962400 A
  • EP 9807695 W
  • EP 97121308 A

Abstract (en)

[origin: WO9929349A1] Transfection particles for delivery of nucleic acid into higher eucaryotic cells in vitro and in vivo comprises one or more nucleic acid molecules condensed by organic cationic molecules. The discrete and stable particles are obtained by complexing the nucleic acid molecules with identical or different organic cartionic precursor molecules without crosslinking nucleic acid molecules, and covalently linking the precursor molecules to each other on the nucleic acid template. For specific cellular targeting, the particles may carry targeting molecules, e.g. sugars. Preferred cationic precursor molecules are lipophilic detergents that are linked to form lipids. The particles contain preferably only one nucleic acid molecule which makes them useful for gene therapy and for delivery of large DNA molecules.

IPC 1-7 (main, further and additional classification)

A61K 47/48

IPC 8 full level (invention and additional information)

A61K 35/76 (2006.01); A61K 47/48 (2006.01); A61K 48/00 (2006.01)

CPC (invention and additional information)

B82Y 5/00 (2013.01); A61K 47/48046 (2013.01); A61K 47/48884 (2013.01)

Citation (search report)

See references of WO 9929349A1

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

EPO simple patent family

WO 9929349 A1 19990617; AR 014054 A1 20010131; AU 1757799 A 19990628; BR 9814255 A 20001010; CA 2312890 A1 19990617; CN 1290178 A 20010404; EE 200000797 A 20020617; EP 0945138 A1 19990929; EP 1037668 A1 20000927; HU 0004322 A2 20010228; HU 0004322 A3 20030428; IL 136418 D0 20010614; JP 2001525378 A 20011211; NO 20002793 A 20000801; NO 20002793 D0 20000531; PL 345849 A1 20020114; SK 8222000 A3 20001211; TR 200001597 T2 20020321; UY 25286 A1 20010131; ZA 9811011 B 19990604

INPADOC legal status

2004-10-20 [18D] DEEMED TO BE WITHDRAWN

- Ref Legal Event Code: 18D

- Effective date: 20040412

2004-01-14 [RAP1] TRANSFER OF RIGHTS OF AN EP PUBLISHED APPLICATION

- Owner name: UNIVERSITE LOUIS PASTEUR DE STRASBOURG

- Ref Legal Event Code: RAP1

2002-10-30 [17Q] FIRST EXAMINATION REPORT

- Ref Legal Event Code: 17Q

- Effective date: 20020913

2000-09-27 [17P] REQUEST FOR EXAMINATION FILED

- Ref Legal Event Code: 17P

- Effective date: 20000704

2000-09-27 [AK] DESIGNATED CONTRACTING STATES:

- Ref Legal Event Code: AK

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE