EP 1037988 A1 20000927 - HUMAN PROTEINS RESPONSIBLE FOR NEDD8 ACTIVATION AND CONJUGATION
Title (en)
HUMAN PROTEINS RESPONSIBLE FOR NEDD8 ACTIVATION AND CONJUGATION
Title (de)
HUMANE PROTEINE VERANTWORTLICH FÜR DIE NEDD8 AKTIVIERUNG UND KONJUGATION
Title (fr)
PROTEINES HUMAINES RESPONSABLES DE L'ACTIVATION ET DE LA CONJUGAISON DE NEDD8
Publication
Application
Priority
- US 9827141 W 19981218
- US 6820997 P 19971219
- US 9652598 P 19980812
Abstract (en)
[origin: WO9932624A1] The invention relates to covalent modification of proteins through their conjugation with other proteins. More particularly, the invention relates to the modulation of such conjugation involving the protein NEDD8. The invention provides compositions and methods for detecting and/or modulating the activation and/or conjugation of NEDD8, as well as compositions and methods for discovering molecules which are useful in detecting and/or modulating the activation and/or conjugation of NEDD8. The present invention arises from the purification and characterization of novel NEDD8 activating and conjugating enzymes.
IPC 1-7
C12N 15/12; C12N 9/00; C07K 14/47; G01N 33/50; C12Q 1/68; C12N 15/11
IPC 8 full level
C07K 14/47 (2006.01); C12N 9/00 (2006.01); C12N 15/09 (2006.01); C12N 15/12 (2006.01); C12P 21/02 (2006.01); C12Q 1/68 (2006.01); G01N 33/50 (2006.01)
CPC (source: EP)
C07K 14/47 (2013.01); C12N 9/00 (2013.01)
Citation (search report)
See references of WO 9932624A1
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9932624 A1 19990701; AU 1935099 A 19990712; AU 758077 B2 20030313; CA 2315240 A1 19990701; EP 1037988 A1 20000927; IL 136873 A0 20010614; JP 2001526890 A 20011225
DOCDB simple family (application)
US 9827141 W 19981218; AU 1935099 A 19981218; CA 2315240 A 19981218; EP 98964164 A 19981218; IL 13687398 A 19981218; JP 2000525543 A 19981218