Global Patent Index - EP 1037994 A1

EP 1037994 A1 20000927 - PEPTIDE ANTAGONISTS OF VASCULAR ENDOTHELIAL GROWTH FACTOR

Title (en)

PEPTIDE ANTAGONISTS OF VASCULAR ENDOTHELIAL GROWTH FACTOR

Title (de)

PEPTID-ANTAGONISTEN DES VASKULAREN ENDOTHELIALEN WACHSTUMSFAKTORS

Title (fr)

PEPTIDES ANTAGONISTES DU FACTEUR DE CROISSANCE DE L'ENDOTHELIUM VASCULAIRE

Publication

EP 1037994 A1 20000927 (EN)

Application

EP 98963815 A 19981209

Priority

  • US 9826103 W 19981209
  • US 6915597 P 19971209
  • US 6968797 P 19971212

Abstract (en)

[origin: WO9929861A1] The present invention provides isolated polypeptides having VEGF antagonist activity, pharmaceutical compositions and methods of treatment. The polypeptides of the invention include polypeptides comprising a portion of SEQ ID NO:1 having VEGF antagonist activity, polypeptides comprising SEQ ID NO:2 or a portion thereof having VEGF antagonist activity, and a polypeptide having the structure of formula (I), set forth above. The present invention further includes analogs and derivatives of these polypeptides having VEGF antagonist activity.

IPC 1-7

C12N 15/19; C07K 14/52; A61K 38/19; A61K 48/00

IPC 8 full level

A61K 31/711 (2006.01); A61K 38/00 (2006.01); A61K 48/00 (2006.01); A61P 9/00 (2006.01); A61P 19/02 (2006.01); A61P 29/00 (2006.01); A61P 35/00 (2006.01); A61P 35/04 (2006.01); A61P 43/00 (2006.01); C07K 14/52 (2006.01); C07K 14/71 (2006.01); C12N 15/09 (2006.01); C12N 15/19 (2006.01)

CPC (source: EP)

A61P 9/00 (2017.12); A61P 19/02 (2017.12); A61P 29/00 (2017.12); A61P 35/00 (2017.12); A61P 35/04 (2017.12); A61P 43/00 (2017.12); C07K 14/71 (2013.01); A61K 38/00 (2013.01); A61K 48/00 (2013.01)

Citation (search report)

See references of WO 9929861A1

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

DOCDB simple family (publication)

WO 9929861 A1 19990617; AU 1810899 A 19990628; AU 1906099 A 19990628; CA 2313390 A1 19990617; EP 1037994 A1 20000927; JP 2001526032 A 20011218; JP 2009148293 A 20090709; JP 4312955 B2 20090812; WO 9930157 A2 19990617; WO 9930157 A3 19990722; WO 9930157 A9 19991021

DOCDB simple family (application)

US 9826103 W 19981209; AU 1810899 A 19981209; AU 1906099 A 19981209; CA 2313390 A 19981209; EP 98963815 A 19981209; JP 2000524433 A 19981209; JP 2009052725 A 20090305; US 9826127 W 19981209