Global Patent Index - EP 1037994 A1

EP 1037994 A1 2000-09-27 - PEPTIDE ANTAGONISTS OF VASCULAR ENDOTHELIAL GROWTH FACTOR

Title (en)

PEPTIDE ANTAGONISTS OF VASCULAR ENDOTHELIAL GROWTH FACTOR

Title (de)

PEPTID-ANTAGONISTEN DES VASKULAREN ENDOTHELIALEN WACHSTUMSFAKTORS

Title (fr)

PEPTIDES ANTAGONISTES DU FACTEUR DE CROISSANCE DE L'ENDOTHELIUM VASCULAIRE

Publication

EP 1037994 A1 (EN)

Application

EP 98963815 A

Priority

  • US 9826103 W
  • US 6915597 P
  • US 6968797 P

Abstract (en)

[origin: WO9929861A1] The present invention provides isolated polypeptides having VEGF antagonist activity, pharmaceutical compositions and methods of treatment. The polypeptides of the invention include polypeptides comprising a portion of SEQ ID NO:1 having VEGF antagonist activity, polypeptides comprising SEQ ID NO:2 or a portion thereof having VEGF antagonist activity, and a polypeptide having the structure of formula (I), set forth above. The present invention further includes analogs and derivatives of these polypeptides having VEGF antagonist activity.

IPC 1-7 (main, further and additional classification)

C12N 15/19; A61K 38/19; A61K 48/00; C07K 14/52

IPC 8 full level (invention and additional information)

C12N 15/09 (2006.01); A61K 31/711 (2006.01); A61K 38/00 (2006.01); A61K 48/00 (2006.01); A61P 9/00 (2006.01); A61P 19/02 (2006.01); A61P 29/00 (2006.01); A61P 35/00 (2006.01); A61P 35/04 (2006.01); A61P 43/00 (2006.01); C07K 14/52 (2006.01); C07K 14/71 (2006.01); C12N 15/19 (2006.01)

CPC (invention and additional information)

C07K 14/71 (2013.01); A61K 38/00 (2013.01); A61K 48/00 (2013.01)

Citation (search report)

See references of WO 9929861A1

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

EPO simple patent family

WO 9929861 A1 19990617; AU 1810899 A 19990628; AU 1906099 A 19990628; CA 2313390 A1 19990617; EP 1037994 A1 20000927; JP 2001526032 A 20011218; JP 2009148293 A 20090709; JP 4312955 B2 20090812; WO 9930157 A2 19990617; WO 9930157 A3 19990722; WO 9930157 A9 19991021

INPADOC legal status


2003-01-02 [18D] DEEMED TO BE WITHDRAWN

- Effective date: 20020702

2000-09-27 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 20000628

2000-09-27 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A1

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE