EP 1038004 A1 20000927 - METHODS FOR INCREASING HEMOPROTEIN PRODUCTION IN FUNGAL MUTANTS
Title (en)
METHODS FOR INCREASING HEMOPROTEIN PRODUCTION IN FUNGAL MUTANTS
Title (de)
VERFAHREN ZUR ERHÖHUNG DER HÄMOPROTEIN-PRODUKTION IN PILZMUTANTEN
Title (fr)
METHODES FAVORISANT LA PRODUCTION D'HEMOPROTEINES DANS DES MUTANTS FONGIQUES
Publication
Application
Priority
- US 9825991 W 19981208
- US 6788697 P 19971208
Abstract (en)
[origin: WO9929874A1] The present invention relates to methods for producing hemoproteins comprising: a) cultivating a mutant of a parent fungal cell in a nutrient medium suitable for production of the hemoprotein, wherein (i) the mutant comprises one or more first nucleic acid sequences comprising a modification of one or more genes encoding one or more heme catabolic enzymes or a control sequence thereof and (ii) the mutant produces less of the one or more heme catabolic enzymes and more of the hemoprotein than the parent cell when cultivated under the same conditions; and b) recovering the hemoprotein from the nutrient medium of the mutant cell.
IPC 1-7
IPC 8 full level
C07K 14/795 (2006.01); C12N 1/15 (2006.01); C12N 9/02 (2006.01); C12N 15/09 (2006.01); C12N 15/53 (2006.01)
CPC (source: EP)
C07K 14/795 (2013.01); C12N 9/001 (2013.01); C12N 9/0083 (2013.01)
Citation (search report)
See references of WO 9929874A1
Designated contracting state (EPC)
AT BE CH DE DK ES FI FR GB GR IE IT LI NL PT SE
DOCDB simple family (publication)
WO 9929874 A1 19990617; AU 1807899 A 19990628; CN 1281510 A 20010124; EP 1038004 A1 20000927; JP 2001526037 A 20011218
DOCDB simple family (application)
US 9825991 W 19981208; AU 1807899 A 19981208; CN 98811984 A 19981208; EP 98962953 A 19981208; JP 2000524445 A 19981208