EP 1038030 A2 20000927 - REAGENTS AND METHODS USEFUL FOR DETECTING DISEASES OF THE PANCREAS
Title (en)
REAGENTS AND METHODS USEFUL FOR DETECTING DISEASES OF THE PANCREAS
Title (de)
REAGENZIEN UND METHODEN GEEIGNET ZUR DETEKTION VON PANKREASE-ERKRANKUNGEN
Title (fr)
REACTIFS ET METHODES S'UTILISANT POUR DETECTER DES AFFECTIONS DU PANCREAS
Publication
Application
Priority
- US 9826441 W 19981211
- US 99056897 A 19971215
Abstract (en)
[origin: WO9931274A2] A set of contiguous and partially overlapping cDNA sequences and polypeptides encoded thereby, designated as PA153 and transcribed from pancreatic tissue, are described. These sequences are useful for the detecting, diagnosing, staging, monitoring, prognosticating, in vivo imaging, preventing or treating, or determining the predisposition of an individual to diseases and conditions of the pancreas, such as pancreatic cancer. Also provided are antibodies which specifically bind to PA153-encoded polypeptide or protein, and agonists or inhibitors which prevent action of the tissue-specific PA153 polypeptide, which molecules are useful for the therapeutic treatment of pancreatic diseases, tumors or metastases.
IPC 1-7
IPC 8 full level
C07K 14/47 (2006.01); C07K 16/18 (2006.01)
CPC (source: EP)
C07K 14/47 (2013.01); C07K 16/18 (2013.01)
Citation (search report)
See references of WO 9931274A2
Designated contracting state (EPC)
AT BE CH DE ES FR GB IT LI NL
DOCDB simple family (publication)
WO 9931274 A2 19990624; WO 9931274 A3 19990902; CA 2315263 A1 19990624; EP 1038030 A2 20000927
DOCDB simple family (application)
US 9826441 W 19981211; CA 2315263 A 19981211; EP 98963112 A 19981211