Global Patent Index - EP 1038030 A2

EP 1038030 A2 2000-09-27 - REAGENTS AND METHODS USEFUL FOR DETECTING DISEASES OF THE PANCREAS

Title (en)

REAGENTS AND METHODS USEFUL FOR DETECTING DISEASES OF THE PANCREAS

Title (de)

REAGENZIEN UND METHODEN GEEIGNET ZUR DETEKTION VON PANKREASE-ERKRANKUNGEN

Title (fr)

REACTIFS ET METHODES S'UTILISANT POUR DETECTER DES AFFECTIONS DU PANCREAS

Publication

EP 1038030 A2 (EN)

Application

EP 98963112 A

Priority

  • US 9826441 W
  • US 99056897 A

Abstract (en)

[origin: WO9931274A2] A set of contiguous and partially overlapping cDNA sequences and polypeptides encoded thereby, designated as PA153 and transcribed from pancreatic tissue, are described. These sequences are useful for the detecting, diagnosing, staging, monitoring, prognosticating, in vivo imaging, preventing or treating, or determining the predisposition of an individual to diseases and conditions of the pancreas, such as pancreatic cancer. Also provided are antibodies which specifically bind to PA153-encoded polypeptide or protein, and agonists or inhibitors which prevent action of the tissue-specific PA153 polypeptide, which molecules are useful for the therapeutic treatment of pancreatic diseases, tumors or metastases.

IPC 1-7 (main, further and additional classification)

C12Q 1/68; C07K 14/47; C07K 16/18; C12N 5/10; G01N 33/574

IPC 8 full level (invention and additional information)

C07K 14/47 (2006.01); C07K 16/18 (2006.01)

CPC (invention and additional information)

C07K 16/18 (2013.01); C07K 14/47 (2013.01)

Citation (search report)

See references of WO 9931274A3

Designated contracting state (EPC)

AT BE CH DE ES FR GB IT LI NL

EPO simple patent family

WO 9931274 A2 19990624; WO 9931274 A3 19990902; CA 2315263 A1 19990624; EP 1038030 A2 20000927

INPADOC legal status


2004-01-07 [18D] DEEMED TO BE WITHDRAWN

- Effective date: 20030701

2001-09-19 [17Q] FIRST EXAMINATION REPORT

- Effective date: 20010807

2000-11-29 [RIN1] INVENTOR (CORRECTION)

- Inventor name: BILLING-MEDEL, PATRICIA, A.

2000-11-29 [RIN1] INVENTOR (CORRECTION)

- Inventor name: COHEN, MAURICE

2000-11-29 [RIN1] INVENTOR (CORRECTION)

- Inventor name: COLPITTS, TRACEY, L.

2000-11-29 [RIN1] INVENTOR (CORRECTION)

- Inventor name: FRIEDMAN, PAULA, N.

2000-11-29 [RIN1] INVENTOR (CORRECTION)

- Inventor name: GORDON, JULIAN

2000-11-29 [RIN1] INVENTOR (CORRECTION)

- Inventor name: GRANADOS, EDWARD, N.

2000-11-29 [RIN1] INVENTOR (CORRECTION)

- Inventor name: HODGES, STEVEN, C.

2000-11-29 [RIN1] INVENTOR (CORRECTION)

- Inventor name: KLASS, MICHAEL, R.

2000-09-27 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 20000524

2000-09-27 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A2

- Designated State(s): AT BE CH DE ES FR GB IT LI NL