Global Patent Index - EP 1039915 A1

EP 1039915 A1 2000-10-04 - CYCLIC PHOSPHONATE ESTER INHIBITORS OF MICROSOMAL TRIGLYCERIDE TRANSFER PROTEIN AND METHOD

Title (en)

CYCLIC PHOSPHONATE ESTER INHIBITORS OF MICROSOMAL TRIGLYCERIDE TRANSFER PROTEIN AND METHOD

Title (de)

CYCLISCHE PHOSPHONATESTER ALS INHIBITOREN DER MICROSOMALEN TRIGLYCERIDTRANSFER PROTEINE UND VERWENDUNGSMETHODE

Title (fr)

INHIBITEURS PHOSPHONATE ESTER CYCLIQUE DE PROTEINE MICROSOMALE DE TRANSFERT DES TRIGLYCERIDES ET PROCEDE ASSOCIE

Publication

EP 1039915 A1 (EN)

Application

EP 98953531 A

Priority

  • US 9821750 W
  • US 6334797 P

Abstract (en)

[origin: WO9921564A1] Novel cyclic phosphonate ester inhibitors of MTP are provided which have structure (I) wherein R<2>, L<2>, A, B, L<1>, R<1> and R<5a> are as set out herein. These compounds are useful in lowering serum cholesterol and triglycerides.

IPC 1-7 (main, further and additional classification)

A61K 31/675; A61K 31/66; C07F 9/58; C07F 9/59; C07F 9/653; C07F 9/6533; C07F 9/6541; C07F 9/6574

IPC 8 full level (invention and additional information)

A61K 31/675 (2006.01); A61K 31/66 (2006.01); A61P 3/04 (2006.01); A61P 3/06 (2006.01); A61P 9/10 (2006.01); A61P 43/00 (2006.01); C07F 9/6571 (2006.01); C07F 9/6574 (2006.01)

CPC (invention and additional information)

C07F 9/657181 (2013.01)

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

EPO simple patent family

WO 9921564 A1 19990506; AU 1087699 A 19990517; AU 753520 B2 20021017; CA 2307889 A1 19990506; EP 1039915 A1 20001004; EP 1039915 A4 20010214; JP 2001521001 A 20011106

INPADOC legal status


2003-10-22 [18D] DEEMED TO BE WITHDRAWN

- Effective date: 20030417

2002-02-13 [17Q] FIRST EXAMINATION REPORT

- Effective date: 20020103

2001-02-14 [A4] SUPPLEMENTARY SEARCH REPORT

- Effective date: 20010104

2001-02-14 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A4

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

2001-02-14 [RIC1] CLASSIFICATION (CORRECTION)

- Free text: 7A 61K 31/675 A, 7A 61K 31/66 B, 7C 07F 9/6574 B, 7C 07F 9/6541 B, 7C 07F 9/6533 B, 7C 07F 9/653 B, 7C 07F 9/59 B, 7C 07F 9/58 B, 7C 07F 9/6571 B, 7C 07F 9/40 B

2000-10-04 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 20000524

2000-10-04 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A1

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE