Global Patent Index - EP 1039929 A1

EP 1039929 A1 2000-10-04 - ACTIVATED T-CELLS AND THEIR USES

Title (en)

ACTIVATED T-CELLS AND THEIR USES

Title (de)

AKTIVIERTEN T-ZELLEN UND DEREN VERWENDUNG

Title (fr)

LYMPHOCYTES ACTIVES ET LEURS UTILISATIONS

Publication

EP 1039929 A1 (EN)

Application

EP 98936862 A

Priority

US 9814715 W

Abstract (en)

[origin: WO9934827A1] The present invention relates to compositions and methods for the treatment or diagnosis of injury of the central nervous system (CNS). In particular, the invention relates to compositions comprising activated T-cells which are used to deliver (a) a diagnostic substance or (b) a therapeutic substance to a site of damage of the CNS caused by injury or disease. The invention also relates to pharmaceutical compositions comprising antiself T-cells that recognize antigens present in a greater concentration in the CNS compared to the circulation and methods of use thereof to prevent or inhibit degeneration of nerves within the CNS. The invention also relates to pharmaceutical compositions comprising an antigen (or derivative thereof) present in a greater concentration in the CNS compared to the circulation (NS-specific antigen or derivative) and methods of use thereof to prevent or inhibit degeneration of nerves within the CNS. The substance-delivering activated T-cell composition of the present invention may be administered alone or in combination with NS-specific T-cells or NS-specific antigen or in combination with NS-specific T-cells and NS-specific antigen.

IPC 1-7 (main, further and additional classification)

A61K 39/35; A01N 63/00; A61K 45/00

IPC 8 full level (invention and additional information)

C12N 15/09 (2006.01); A61K 35/28 (2006.01); A61K 38/00 (2006.01); A61K 38/17 (2006.01); A61K 39/00 (2006.01); A61K 49/00 (2006.01); A61K 51/00 (2006.01); A61P 9/10 (2006.01); A61P 17/02 (2006.01); A61P 21/02 (2006.01); A61P 25/14 (2006.01); A61P 25/16 (2006.01); A61P 25/28 (2006.01); A61P 27/06 (2006.01); C12N 5/10 (2006.01); A61K 35/12 (2006.01); A61K 48/00 (2006.01)

CPC (invention and additional information)

A61K 39/0007 (2013.01); A61K 38/1709 (2013.01); A61K 35/12 (2013.01); A61K 48/00 (2013.01); A61K 2039/5158 (2013.01)

Citation (search report)

See references of WO 9934827A1

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

EPO simple patent family

WO 9934827 A1 19990715; EP 1039929 A1 20001004; JP 2002500199 A 20020108

INPADOC legal status


2004-06-16 [18W] WITHDRAWN

- Effective date: 20040422

2000-10-04 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 20000202

2000-10-04 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A1

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

2000-10-04 [AX] REQUEST FOR EXTENSION OF THE EUROPEAN PATENT TO

- Free text: AL PAYMENT 20000202;LT PAYMENT 20000202;LV PAYMENT 20000202;MK PAYMENT 20000202;RO PAYMENT 20000202;SI PAYMENT 20000202