EP 1041882 A4 20020417 - TRANSVASCULAR DELIVERY OF A COMPOSITION TO AN EXTRAVASCULAR TISSUE OF A MAMMAL
Title (en)
TRANSVASCULAR DELIVERY OF A COMPOSITION TO AN EXTRAVASCULAR TISSUE OF A MAMMAL
Title (de)
TRANSVASKULÄRE VERABREICHUNG EINER ZUSAMMENSETZUNG AN EIN EXTRAVASKULÄRES GEWEBE EINES SÄUGETIERES
Title (fr)
ACHEMINEMENT TRANSVASCULAIRE D'UNE COMPOSITION VERS UN TISSU EXTRAVASCULAIRE D'UN MAMMIFERE
Publication
Application
Priority
- US 9827072 W 19981218
- US 6831797 P 19971219
Abstract (en)
[origin: WO9931982A1] Compositions, methods, kits and apparatus are provided for delivering a macromolecular assembly such as a plasmid, virus vector, or other gene vector, to an extravascular tissue such as muscle tissue. The composition comprises the macromolecular assembly and a vascular permeability-enhancing agent. In another embodiment, the composition further comprises a vasodilating agent. The method of the invention comprises proving a vascular permeability-enhancing agent to a blood vessel and providing a macromolecular assembly to the vessel. An oxygenator useful for providing oxygen to a fluid extracorporeally prior to providing the fluid to a blood vessel of a mammal is included in the invention. Kits, apparatus, and methods for using the catheters described herein for isolating cardiac ciruclation, diverting caval blood flow from the right atrium, and other purposes, are also described.
IPC 1-7
IPC 8 full level
A61M 25/00 (2006.01); A61K 35/76 (2006.01); A61K 38/00 (2006.01); A61K 38/04 (2006.01); A61K 38/18 (2006.01); A61K 38/19 (2006.01); A61K 38/20 (2006.01); A61K 38/22 (2006.01); A61K 38/43 (2006.01); A61K 45/00 (2006.01); A61K 45/06 (2006.01); A61K 48/00 (2006.01); A61M 1/36 (2006.01); A61P 9/00 (2006.01); C07K 14/475 (2006.01); A61M 1/16 (2006.01)
CPC (source: EP US)
A61K 38/1709 (2013.01 - EP); A61K 38/1866 (2013.01 - EP); A61K 45/06 (2013.01 - EP); A61K 48/00 (2013.01 - EP); A61M 1/36 (2013.01 - EP); A61M 1/3613 (2013.01 - EP US); A61M 1/3621 (2013.01 - EP US); A61M 1/3659 (2014.02 - EP US); A61P 9/00 (2018.01 - EP); A61M 1/1698 (2013.01 - EP)
C-Set (source: EP)
Citation (search report)
- [X] US 5478309 A 19951226 - SWEEZER WILLIAM P [US], et al
- [X] US 5433700 A 19950718 - PETERS WILLIAM S [AU]
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9931982 A1 19990701; AU 2201399 A 19990712; AU 774299 B2 20040624; CA 2314905 A1 19990701; EP 1041882 A1 20001011; EP 1041882 A4 20020417; JP 2001526071 A 20011218; JP 4299967 B2 20090722
DOCDB simple family (application)
US 9827072 W 19981218; AU 2201399 A 19981218; CA 2314905 A 19981218; EP 98966022 A 19981218; JP 2000524995 A 19981218