EP 1041986 A1 20001011 - PHARMACEUTICALLY ACTIVE COMPOUND AND METHODS OF USE
Title (en)
PHARMACEUTICALLY ACTIVE COMPOUND AND METHODS OF USE
Title (de)
PHARMAZEUTISCH AKTIVE VERBINDUNG UND VERFAHREN ZUR VERWENDUNG
Title (fr)
COMPOSE ACTIF DU POINT DE VUE PHARMACEUTIQUE ET SES METHODES D'UTILISATION
Publication
Application
Priority
- US 9821395 W 19981009
- US 6346997 P 19971010
Abstract (en)
[origin: WO9918962A1] The present invention relates to racemic and optically active N-(2-chloro-5- methylthiophenyl) -N'-(3- methylsulfinylphenyl) -N'-methylguanidine, N-(2-chloro-5- methylsulfinylphenyl) -1-(7-trifluoromethyl -1,2,3,4- tetrahydroquinolinyl) carboximidamide, and N-(3-methylsulfinylphenyl) -N-methyl-N'- (2-chloro-5- methoxyphenyl) guanidine and pharmaceutically acceptable salts thereof, and pharmaceutical compositions and therapeutic methods of treatment that comprise such compounds. Compounds of the invention are particularly useful for the treatment or prophylaxis of neurological injury and neurodegenerative disorders.
IPC 1-7
IPC 8 full level
A61K 31/155 (2006.01); A61K 31/47 (2006.01); A61P 1/08 (2006.01); A61P 9/00 (2006.01); A61P 25/00 (2006.01); A61P 25/04 (2006.01); A61P 25/06 (2006.01); A61P 25/08 (2006.01); A61P 25/14 (2006.01); A61P 25/16 (2006.01); A61P 25/28 (2006.01); A61P 27/02 (2006.01); A61P 31/04 (2006.01); A61P 43/00 (2006.01); C07C 323/44 (2006.01); C07D 215/12 (2006.01); C07D 215/48 (2006.01)
CPC (source: EP KR)
A61K 31/47 (2013.01 - KR); A61P 1/08 (2017.12 - EP); A61P 9/00 (2017.12 - EP); A61P 25/00 (2017.12 - EP); A61P 25/04 (2017.12 - EP); A61P 25/06 (2017.12 - EP); A61P 25/08 (2017.12 - EP); A61P 25/14 (2017.12 - EP); A61P 25/16 (2017.12 - EP); A61P 25/28 (2017.12 - EP); A61P 27/02 (2017.12 - EP); A61P 31/04 (2017.12 - EP); A61P 43/00 (2017.12 - EP); C07C 323/44 (2013.01 - EP); C07D 215/48 (2013.01 - EP)
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9918962 A1 19990422; AU 1076799 A 19990503; CA 2306276 A1 19990422; EP 1041986 A1 20001011; EP 1041986 A4 20010321; JP 2001519393 A 20011023; KR 100761451 B1 20070927; KR 20010031007 A 20010416
DOCDB simple family (application)
US 9821395 W 19981009; AU 1076799 A 19981009; CA 2306276 A 19981009; EP 98953372 A 19981009; JP 2000515597 A 19981009; KR 20007003793 A 20000407