EP 1042459 A4 20030723 - BIFUNCTIONAL MOLECULES
Title (en)
BIFUNCTIONAL MOLECULES
Title (de)
BIFUNKTIONELLE MOLEKÜLE
Title (fr)
MOLECULES BIFONCTIONNELLES
Publication
Application
Priority
- AU 9801076 W 19981224
- AU PP111097 A 19971224
- AU PP517698 A 19980811
Abstract (en)
[origin: WO9933965A1] A chimeric antibody conjugate comprising an antigen binding region of a non-human antibody and an immunoglobulin constant region which comprises at least one CH domain or epitope thereof, with the proviso that the constant region is not a naturally occurring FC fragment. A bifunctional molecule for use in labelling an antibody derived from a first species, the bifunctional molecule comprising a binding region which binds to the antibody of the first species or to one or more groups provided thereon, and a constant region derived from an antibody of a second species, the constant region comprising at least one CH domain or an epitope thereof. The present invention relates to bifunctional molecules and complexes which are useful as positive control reagents in antibody based diagnostic tests. The present invention also relates to polynucleotides encoding these bifunctional molecules, and to diagnostic assays involving the use of these molecules.
IPC 1-7
IPC 8 full level
C12N 15/09 (2006.01); C07K 14/31 (2006.01); C07K 14/36 (2006.01); C07K 16/08 (2006.01); C07K 16/10 (2006.01); C07K 16/12 (2006.01); C07K 16/18 (2006.01); C07K 19/00 (2006.01)
CPC (source: EP US)
C07K 14/31 (2013.01 - EP US); C07K 14/36 (2013.01 - EP US); C07K 16/10 (2013.01 - EP US); C07K 16/1081 (2013.01 - EP US); C07K 16/18 (2013.01 - EP US); C07K 2317/24 (2013.01 - EP US); C07K 2317/52 (2013.01 - EP US); C07K 2317/622 (2013.01 - EP US); C07K 2319/00 (2013.01 - EP US)
Citation (search report)
- [XA] WO 9727486 A1 19970731 - ABBOTT LAB [US]
- [XA] EP 0617127 A1 19940928 - TANOX BIOSYSTEMS INC [US]
- [XA] DATABASE WPI Section Ch Week 199049, Derwent World Patents Index; Class B04, AN 1990-365934, XP002241370
- See also references of WO 9933965A1
Designated contracting state (EPC)
AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE
DOCDB simple family (publication)
WO 9933965 A1 19990708; CA 2315944 A1 19990708; EP 1042459 A1 20001011; EP 1042459 A4 20030723; JP 2002508933 A 20020326; US 2006024766 A1 20060202; US 7026446 B1 20060411
DOCDB simple family (application)
AU 9801076 W 19981224; CA 2315944 A 19981224; EP 98960932 A 19981224; JP 2000526623 A 19981224; US 12369605 A 20050505; US 58192400 A 20000619